Clinical Facial Composite Tissue Allotransplantation: A Review of the Global Experience and Future Implications

  • Helen G. Hui-Chou
  • Eduardo D. Rodriguez


Since 2005, 11 facial composite tissue allotransplantations (CTA) have been performed in 8 different centers in 6 countries. Five teams have reported their work and outcomes in separate publications. We review in detail the first four global experiences and compare indications, donor/recipient matching criteria, CTA graft anatomy, immunosuppressive protocols, and postoperative course. A thorough review of the eight publications by five transplantation groups was conducted. Additional information gathered from official press releases were also included for review. Some details of the remaining transplants are also discussed to facilitate evaluation of indications, matching criteria and future directions for facial CTA.


Human Leukocyte Antigen Acute Rejection Mycophenolate Mofetil Chronic Rejection Skin Tone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.





Composite Tissue Allotransplantation


Epstein–Barr Virus




Graft vs. Host disease


Nerve Conduction Studies


Pressure-Specified Sensory Device


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Copyright information

© Springer London 2011

Authors and Affiliations

  1. 1.Division of Plastic and Reconstructive SurgeryThe Johns Hopkins Hospital/University of Maryland School of MedicineBaltimoreUSA

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