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Clinical Facial Composite Tissue Allotransplantation: A Review of the Global Experience and Future Implications

  • Helen G. Hui-Chou
  • Eduardo D. Rodriguez
Chapter

Abstract

Since 2005, 11 facial composite tissue allotransplantations (CTA) have been performed in 8 different centers in 6 countries. Five teams have reported their work and outcomes in separate publications. We review in detail the first four global experiences and compare indications, donor/recipient matching criteria, CTA graft anatomy, immunosuppressive protocols, and postoperative course. A thorough review of the eight publications by five transplantation groups was conducted. Additional information gathered from official press releases were also included for review. Some details of the remaining transplants are also discussed to facilitate evaluation of indications, matching criteria and future directions for facial CTA.

Keywords

Human Leukocyte Antigen Acute Rejection Mycophenolate Mofetil Chronic Rejection Skin Tone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

CMV

Cytomegalovirus

CTA

Composite Tissue Allotransplantation

EBV

Epstein–Barr Virus

EMG

Electromyelography

GVHD

Graft vs. Host disease

NCS

Nerve Conduction Studies

PSSD

Pressure-Specified Sensory Device

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Copyright information

© Springer London 2011

Authors and Affiliations

  1. 1.Division of Plastic and Reconstructive SurgeryThe Johns Hopkins Hospital/University of Maryland School of MedicineBaltimoreUSA

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