Classification of Face Rejection: Banff classification for CTA

  • Jean Kanitakis
  • Linda C. Cendales


Facial allotransplantation (FA) has recently emerged as a new viable option for reconstruction of severe facial tissue defects that are not amenable to conventional reconstructive techniques. FA falls within the spectrum of Composite Tissue Allografts (CTA), and as such may undergo allograft rejection. The experience obtained so far from the limited number of FA shows that the recipients develop, in the first post-graft months, signs of (skin) rejection that can be reversed with adjustment of the immunosuppressive treatment. The severity of skin rejection can be assessed with a pathological score that was proposed during the 2007 Banff meeting in La Coruna, Spain (Banff CTA-07) and classifies rejection in five grades (0–IV) according to the severity of pathological changes in the skin. There are still several questions that remain so far unanswered regarding rejection in FA, including namely the role of skin-infiltrating cells and the possibility of development of chronic rejection.


Acute Rejection Oral Mucosa Allograft Rejection Allergic Contact Dermatitis Chronic Rejection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Antibody-mediated rejection


Composite tissue allografts


Facial allotransplantation


Graft versus host disease




Periodic Acid Schiff stain


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Copyright information

© Springer London 2011

Authors and Affiliations

  1. 1.Department of Dermatology/Laboratory of DermatopathologyEdouard Herriot Hospital GroupLyonFrance

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