Candidate Gene Association Studies in Stroke

  • Elizabeth G. Holliday
  • Christopher J. Oldmeadow
  • Jane M. Maguire
  • John Attia


This chapter describes the strategy of association studies that can be used to characterize the genetics of stroke. It explains advantages and disadvantages of the method and discusses current evidence of the genes that have been associated with stroke.


Ischemic Stroke Population Stratification Genetic Association Study MTHFR Gene Mendelian Randomization 
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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Elizabeth G. Holliday
    • 1
  • Christopher J. Oldmeadow
    • 2
  • Jane M. Maguire
    • 3
  • John Attia
    • 4
  1. 1.Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of HealthUniversity of NewcastleCallaghanAustralia
  2. 2.School of Medicine and Public Health, Faculty of HealthUniversity of NewcastleNewcastleAustralia
  3. 3.School of Nursing and MidwiferyUniversity of NewcastleCallaghanAustralia
  4. 4.Department of MedicineJohn Hunter Hospital, University of NewcastleNew LambtonAustralia

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