Fisher and natural selection (1922)


In 1922 the British mathematical biologist Ronald Fisher published a very influential article on population genetics. This chapter considers only one section of the article, which focuses on a variant of the Hardy–Weinberg model including natural selection. Fisher showed that if the heterozygote is favoured, then both alleles can coexist. If one of the two homozygotes is favoured, then the other allele disappears. The underlying problem is that of explaining why some genes can have several alleles.


Natural Selection Survival Probability Genetical Theory Investment Company Dominance Ratio 
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Further reading

  1. 1.
    Fisher Box, J.: R.A. Fisher, The Life of a Scientist. John Wiley & Sons, New York (1978) Google Scholar
  2. 2.
    Fisher, R.A.: On the dominance ratio. Proc. R. Soc. Edinb. 42, 321–341 (1922). Google Scholar
  3. 3.
    Fisher, R.A.: The Genetical Theory of Natural Selection. Clarendon Press, Oxford (1930). MATHGoogle Scholar
  4. 4.
    Yates, F., Mather, K.: Ronald Aylmer Fisher 1890–1962. Biog. Mem. Fellows R. Soc. 9, 91–120 (1963). CrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  1. 1.IRD (Institut de Recherche pour le Développement)BondyFrance

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