Summary
A simple mathematical model is proposed to study the influence of cell fission on transport. The model describes fractional tumor development, which is a one-dimensional continuous time random walk (CTRW). An answer to the question of how the malignant neoplasm cells appear at an arbitrary distance from the primary tumor is proposed. The model is a possible consideration for diffusive cancers as well. A chemotherapy influence on the CTRW is studied by an observation of stationary solutions.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bahish, J.W., Jain, R.K.: Fractals and cancer. Cancer Research, 60, 3683–3688 (2000).
Baskin, E.M., Iomin, A.: Superdiffusion on a comb structure. Phys. Rev. Lett., 93, 120603 (2004).
Bellomo, N., Preziosi, L.: Modelling and mathematical problems related to tumor evolution and its interaction with the immune system. Math. Comput. Modelling, 32, 413–452 (2000).
Gorenflo, R., Mainardi, F.: Fractional diffusion process: probability distributions and continuous time random walk. In: Processes With Long Range Correlations, pp. 148–166. Springer-Verlag, Berlin, (2003).
Gottlieb, M.E.: Vascular networks: fractal anatomies from non-linear physiologies. IEEE Eng. Med. Bio. Mag., 13, 2196 (1991).
Hilfer, R. (ed): Fractional Calculus in Physics. World Scientific, Singapore, (2000).
Iomin, A.: Superdiffusion of cancer on a comb structure. J. Phys.: Conference Series, 7, 57–67 (2005).
Iomin, A.: Fractional transport of tumor cells. WSEAS Trans. Biol. Biomed., 2, 82–86 (2005)
Janke, E., Emde, F., Löosh, F.: Tables of Higher Functions. McGraw-Hill, New York, (1960).
Kamke, E.: Differentialgleichungen: Löosungen. Leipzig, (1959).
Keleg, S., BĂĽuchler, P., Ludwig, R., BĂĽuchler, M.W., Friess, H.: Invasion and metastasis in pancreatic cancer. Molecular Cancer, 2:14, (2003) .
Klafter, J., Blumen, A., Slesinger, M.F.: Stochastic pathway to anomalous diffusion. Phys. Rev. A, 35, 3081–3085 (1987).
Mainardi, F.: Fractional relaxation-oscillation and fractional diffusion-wave phenomena. Chaos Solitons Fractals, 7, 1461–1477 (1996).
Mantzaris, N.V., Webb, S., Othmer, H.G.J.: Mathematical modeling of tumor-induced angiogenesis. Math. Biol., 49, 111–187 (2004).
McDougall, S.R., Anderson, A.R.A., Chaplain, M.A.J., Sherratt, J.A.: Mathematical modelling of flow through vascular networks: implications for tumour-induced angiogenesis and chemotherapy strategies. Bull. Math. Biol. 64, 673–702 (2002).
Metzler, R., Klafter, J.: The random walk’s guide to anomalous diffusion: a fractional dynamics approach. Phys. Rep., 339, 1–77 (2000).
Montroll, E.W., Weiss, G.H.: Random walks on lattices, II. J. Math. Phys., 6, 167–181 (1965).
Murray, J.D.: Mathematical Biology, Springer, Heidelberg1993).
Podlubny, I.: Fractional Differential Equations, Academic Press, San Diego1999).
Sherratt, J.A., Perumpanani, A.J., Owen, M.R.: Pattern formation. In: cancer, in On Growth and Form, Editors: Chaplain, M.A.J., Singh, G.D., McLachlan, J.C., pp. 47–73. Wiley, Chichester1999).
Swanson, K.R., Bridge, S., Murray, J.D., Alvord, Jr, E.S.: Virtual and real brain tumors: using mathematical modeling to quantify glioma growth and invasion. J. Neurol. Sci., 216, 1–10 (2003).
Weiss, G.H., Havlin, S.: Some properties of a random-walk on a comb structure. Physica A, 134, 474–482 (1984).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 springer
About this chapter
Cite this chapter
Iomin, A. (2007). Fractional Transport of Cancer Cells Due to Self-Entrapment by Fission. In: Deutsch, A., Brusch, L., Byrne, H., Vries, G.d., Herzel, H. (eds) Mathematical Modeling of Biological Systems, Volume I. Modeling and Simulation in Science, Engineering and Technology. Birkhäuser Boston. https://doi.org/10.1007/978-0-8176-4558-8_17
Download citation
DOI: https://doi.org/10.1007/978-0-8176-4558-8_17
Publisher Name: Birkhäuser Boston
Print ISBN: 978-0-8176-4557-1
Online ISBN: 978-0-8176-4558-8
eBook Packages: Mathematics and StatisticsMathematics and Statistics (R0)