Mechanical Properties of Human Mineralized Connective Tissues

  • R. De Santis
  • L. Ambrosio
  • F. Mollica
  • P. Netti
  • L. Nicolais
Part of the Modeling and Simulation in Science, Engineering and Technology book series (MSSET)


Experimental work has to be tightly linked with modeling. In fact, successful modeling requires firstly comparison with experiments in order to verify its predictions or to set its range of validity. Secondly, experiments measuring the mechanical properties of tissues are needed as input to calibrate mechanical models of organs that can be used to run simulations in silico. In this chapter we wish to provide a comprehensive literature review covering the mechanical characterization of hard tissues, in particular compact bone, trabecular bone and dentine

Elastic and strength properties of such tissues are carefully reviewed, together with fracture mechanics properties when available. Properties obtained from different measurement devices are gathered and compared with each other. The anisotropy and the inelasticity of the mechanical properties of hard tissues is particularly stressed


Elastic Modulus Atomic Force Microscopy Fracture Toughness Cortical Bone Trabecular Bone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Boston 2007

Authors and Affiliations

  • R. De Santis
    • 1
  • L. Ambrosio
    • 1
  • F. Mollica
    • 2
  • P. Netti
    • 3
  • L. Nicolais
    • 3
  1. 1.IMCB Institute for Composite and Biomedical Materials National Research CouncilNapoliItaly
  2. 2.Department of EngineeringUniversity of FerraraFerraraItaly
  3. 3.Department of Materials and Production EngineeringUniversity of Naples “Federico II”NapoliItaly

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