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Anatomy and Histology of the Penile and Clitoral Prepuce in Primates

An Evolutionary Perspective of the Specialised Sensory Tissue of the External Genitalia
  • Christopher J. Cold
  • Kenneth A. McGrath

Abstract

For various reasons, penile and clitoral prepuces have been amputated from children in certain human societies for thousands of years. Although the justifications for male and female circumcision have changed over the last several thousand years, the practice of circumcision has not been examined from the perspective of primate evolution. Why do primates have a prepuce, and what function does it have? The comparative anatomy between human and non-human primates will be reviewed with a specific focus on the sensory innervation of the prepuce and glans.

Keywords

Sexual Selection External Genitalia Sensory Innervation Female Circumcision Glans Penis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Martin RD. Primate Origins and Evolution: A Phylogenetic Reconstruction. Princeton, New Jersey: Princeton University Press 1990.Google Scholar
  2. 2.
    Diamond J. Why Sex is Fun: The Evolution of Human Sexuality. London: Weidenfeld & Nicolson. 1997.Google Scholar
  3. 3.
    Dogiel AS. Die Nervenendigungen in der Schleimhaut der aüsseren Genitalorgane des Menschen. Arch Mikr.-Anat Forsch 1893;41:585–612.Google Scholar
  4. 4.
    Dogiel AS. Über die Nervenendapparate in der Haut des Menschen. Ztschr Wiss Zoo1 1903;75:46–111.Google Scholar
  5. 5.
    Ohmori D. Über die Entwicklung der Innervation der Genitalapparate als peripheren Aufnahme-Apparat der genitalen Reflex. Z Anat Entw.-Gesch 1924;70:347–410.CrossRefGoogle Scholar
  6. 6.
    Yamada K. Studies in the innervation in tenth month human embryo. Tohoku J Exper Med 1951;54:151.CrossRefGoogle Scholar
  7. 7.
    Yamada K. On the sensory nerve terminations in clitoris in human adult. Tohoku J Exper Med 1951;54:163–74.Google Scholar
  8. 8.
    Winkleman RK. The cutaneous innervation of human newborn prepuce. J Invest Derm 1956;26:53–67.Google Scholar
  9. 9.
    Winkelmann RK. The mucocutaneous end-organ. Arch Dermatol 1957;76:225–35.Google Scholar
  10. 10.
    Krantz KE. Innervation of the human vulva and vagina: a microscopic study. Obstet Gynecol 1958;12:382–96.PubMedGoogle Scholar
  11. 11.
    Winkelmann RK. The erogenous zones: their nerve supply and significance. Proc Mayo Clin 1959:34:39–47.Google Scholar
  12. 12.
    Butler AB, Hodos W. Comparative Vertebrate Neuroanatomy: Evolution and Adaptation. New York: Wiley-Liss. 1996.Google Scholar
  13. 13.
    Stenn KS, Bhawan J. The normal histology of the skin. In: Farmer ER, Hood AF, eds. Pathology of the Skin. Norwalk, CT: Appleton and Lange. 1990.Google Scholar
  14. 14.
    Stenn KS, Bhawan J. The normal histology of the skin. In: Farmer ER, Hood AF, eds. Pathology of the Skin. Norwalk, CT: Appleton and Lange. 1990.Google Scholar
  15. 15.
    Stenn KS, Bhawan J. The normal histology of the skin. In: Farmer ER, Hood AF, eds. Pathology of the Skin. Norwalk, CT: Appleton and Lange. 1990.Google Scholar
  16. 16.
    Taylor JR. The prepuce: What, exactly, is removed by circumcision: a preliminary report. In: Milos M, Richter L, Hodges F, eds. Proceedings of the Second International Symposium on Circumcision. 1991. San Anselmo: NOCIRC. 1994.Google Scholar
  17. 17.
    Taylor JR, Lockwood AP, Taylor AJ. The prepuce: specialized mucosa of the penis and its loss to circumcision. Br J Urol 1996;77:291–5.PubMedGoogle Scholar
  18. 18.
    Cold C, Tarara R. Penile and clitoral prepuce mucocutaneous receptors in macaca mulatta. Vet Pathol 1997;34:506.Google Scholar
  19. 19.
    Halata Z, Munger B. The neuroanatomical basis for the protopathic sensibility of the human glans penis. Brain Res 1986;371:205–30.PubMedCrossRefGoogle Scholar
  20. 20.
    Halata Z, Spaethe A. Sensory innervation of the human penis. In: Ivell & Holstein, eds. The Fate of the Male Germ Cell. New York: Plenum Press. 1997.Google Scholar
  21. 21.
    Von Frey M. Beitrage zur physiologie des schmerzsinns. Akad Wiss Leipzig Math.-Naturwiss Kl Ber 1894;46:185–96,283–96.Google Scholar
  22. 22.
    Head H. Studies in Neurology. London: Oxford University Press. 1920.Google Scholar
  23. 23.
    Taylor JR, Lockwood AP, Taylor AJ. The prepuce: specialized mucosa of the penis and its loss to circumcision. Br J Urol 1996;77:291–5.PubMedGoogle Scholar
  24. 24.
    Winkelmann RK. The erogenous zones: their nerve supply and significance. Proc Mayo Clin 1959:34:39–47.Google Scholar
  25. 25.
    Desrochers A, St. Jean G, Anderson DE. Surgical management of preputial injuries in Bulls: 51 cases (1986–1994). Can Vet J 1995;36:553–6.PubMedGoogle Scholar
  26. 26.
    Lumia AR, Sachs BD, Meisel RL. Sexual reflexes in male rats: restoration of ejaculation following suppression by penile sheath removal. Physiol Behavior 1979;23:273–7.CrossRefGoogle Scholar
  27. 27.
    Laumann EO, Masi CM, Zuckerman EW. Circumcision in the United States: prevalence, prophylactic effects, and sexual practice. JAMA 1997;277:1052–7.PubMedCrossRefGoogle Scholar
  28. 28.
    Money J, Davison J. Adult penile circumcision: erotosexual and cosmetic sequelae. J Sex Res 1983;19:289–92.CrossRefGoogle Scholar
  29. 29.
    Halata Z, Munger B. The neuroanatomical basis for the protopathic sensibility of the human glans penis. Brain Res 1986;371:205–30.PubMedCrossRefGoogle Scholar
  30. 30.
    Van Howe RS, Cold CJ. Advantages and disadvantages of neonatal circumcision. JAMA 1997;278:203.PubMedCrossRefGoogle Scholar
  31. 31.
    Taddio A, Goldbach M, Ipp M, Stevens B, Koren G. Effect of neonatal circumcision on pain responses during vaccination in boys. Lancet 1995;345:291–2.PubMedCrossRefGoogle Scholar
  32. 32.
    Taddio A, Katz J, Ilersich AL, Koren G. Effects of neonatal circumcision on pain response during subsequent routine vaccination. Lancet 1997;349:599–603.PubMedCrossRefGoogle Scholar
  33. 33.
    Wall PD, Melzack R. Textbook of Pain. 2nd ed. Edinburgh: Churchill Livingstone. 1989.Google Scholar
  34. 34.
    Cold CJ, Taylor JR. The prepuce. Br J Urol Circumcision Supplement. In pressGoogle Scholar
  35. 35.
    Moldwin RM, Valderrama E. Immunohistochemical analysis of nerve distribution patterns within preputial tissue. J Urol 1989;141:499A.Google Scholar
  36. 36.
    Desrochers A, St. Jean G, Anderson DE. Surgical management of preputial injuries in bulls: 51 cases (1986–1994). Can Vet J 1995;36:553–6.PubMedGoogle Scholar
  37. 37.
    Darwin CR. Origin of Species by Means of Natural Selection (1859). Chicago: Encyclopedia Britannica. 1952:40.Google Scholar
  38. 38.
    Darwin CR. The Descent of Man and Selection in Relation to Sex. London: Murray. 1871.Google Scholar
  39. 39.
    Harcourt AH. Sexual selection and sperm competition in primates: what are male genitalia good for? Evolutionary Anthropol 1995;4:121–9.CrossRefGoogle Scholar
  40. 40.
    Hanison RM, Lewis RW. The male reproductive tract and its fluids. In: Dukelow WR, Erwin J, eds. Reproduction and Development. In: Comparative Primate Biology. Vol. 3. New York: Liss 1986.Google Scholar
  41. 41.
    Soliman AH. A Comparative Study of the Female Genital System of Mammalia [MD thesis]. Cairo, Egypt: Department of Anatomy, Cairo University. 1956.Google Scholar
  42. 42.
    Diamond J. Why Sex is Fun: The Evolution of Human Sexuality. London: Weidenfeld & Nicolson. 1997.Google Scholar
  43. 43.
    Diamond J. Why Sex is Fun: The Evolution of Human Sexuality. London: Weidenfeld & Nicolson. 1997.Google Scholar
  44. 44.
    Martin DE, Gould KG. The male ape genital tract and its secretions. In: Graham CE, ed. Reproductive Biology of the Great Apes: Comparative and Biomedical Perspectives. New York: Academic Press 1981.Google Scholar
  45. 45.
    Izor RJ, Walchuk SL, Wilkms L. Anatomy and systematic significance of the penis of the pygmy chimpanzee, Pan paniscus. Folia Primatologica 1981;35:218–24.CrossRefGoogle Scholar
  46. 46.
    Champion RH, Wegrzyn J. Congenital os penis J Urol 1964;91:663–4.PubMedGoogle Scholar
  47. 47.
    Gelbard MK. Dystrophic penile calcification in Peyronie’s disease. J Urol 1988;139:738–4.PubMedGoogle Scholar
  48. 48.
    Hoeg OM. Human penile ossification. Scand J Urol Nephrol 1986;20:231–2.PubMedGoogle Scholar
  49. 49.
    Harcourt AH. Sexual selection and sperm competition in primates: what are male genitalia good for? Evolutionary Anthropol 1995;4:121–9.CrossRefGoogle Scholar
  50. 50.
    Harcourt AH, Gardiner J. What are spiney penises for? Functional anatomy in primates. XIVth Congress of the International Primatological Society. Strasbourg: IPS. 1992.Google Scholar
  51. 51.
    Hershkovitz P. Male external genitalia of non-prehensile tailed south american monkeys. Part 1. Sub-family Pitheciinae, Family Cebidae. Fieldiana: Zoology 1993;73. [Publication 1451, Sept. 30,1993.]Google Scholar
  52. 52.
    Harrison RM, Lewis RW. The male reproductive tract and its fluids. In: Dukelow WR, Erwin J, eds. Reproduction and Development. In: Comparative Primate Biology. Vol. 3. New York: Liss. 1986.Google Scholar
  53. 53.
    Hershkovitz P. Male external genitalia of non-prehensile tailed south american monkeys Part 1. Subfamily Pitheciinae, Family Cebidae. Fieldiana: Zoology 1993;73. [Publication 1451, Sept. 30,1993.]Google Scholar
  54. 54.
    Diamond J. Why Sex is Fun: The Evolution of Human Sexuality. London: Weidenfeld & Nicolson. 1997.Google Scholar
  55. 55.
    Darwin CR. The Descent of Man and Selection in Relation to Sex. London: Murray. 1871.Google Scholar
  56. 56.
    Short RV. Sexual selection in man and the great apes. In: Graham CE, ed. Reproductive Biology of the Great Apes: Comparative and Biomedical Perspectives. New York: Academic Press. 1981.Google Scholar
  57. 57.
    Dixson AF. Sexual selection and the evolution of copulatory behavior in nocturnal prosimians. In: Alterman L, Doyle GA, eds Creatures of the Dark The Nocturnal Prosimians. New York: Plenum Press. 1995.Google Scholar
  58. 58.
    Soliman AH. A Comparative Study of the Female Genital System of Mammalia [MD thesis]. Cairo, Egypt: Department of Anatomy, Cairo University. 1956.Google Scholar
  59. 59.
    Dixson AF, NJ Mundy. Sexual behavior, sexual swelling, and penile evolution in chimpanzees (Pan troglodytes). Arch Sex Behav 1994;23:267–80.PubMedCrossRefGoogle Scholar
  60. 60.
    Remondino PC. History of Circumcision from the Earliest Times to the Present: Moral and Physical Reasons for its Performance. Philadelphia: FA Davis Company Publishers. 1891.Google Scholar
  61. 61.
    Remondino PC. History of Circumcision from the Earliest Times to the Present: Moral and Physical Reasons for its Performance. Philadelphia: FA Davis Company Publishers. 1891:206–7.Google Scholar
  62. 62.
    Remondino PC. History of Circumcision from the Earliest Times to the Present: Moral and Physical Reasons for its Performance. Philadelphia: FA Davis Company Publishers 1891:206–7.Google Scholar
  63. 63.
    Schoen EJ. The circumcision decision. Moment 1997;22:44–6,68–9. [here, p. 69.]Google Scholar
  64. 64.
    Talbot ES. Inheritance of circumcision effects. Medicine 1898;4:473–5.Google Scholar
  65. 65.
    Duckett JW, Keating MA. Technical challenge of the megameatus intact prepuce hypospadias variant: the pyramid procedure. J Urol 1989;141:1407–9.PubMedGoogle Scholar
  66. 66.
    Attalla MF. Subcoronal hypospadias with complete prepuce: a distinct entity and new procedure for repair. Br J Plust Surg 1991;44:122–5.CrossRefGoogle Scholar
  67. 67.
    Cox G. De Virginibus puerisque: The function of the human foreskin considered from an evolutionary perspective. Med Hypotheses 1995;45:617–21.PubMedCrossRefGoogle Scholar
  68. 68.
    Laumann EO, Masi CM, Zuckerman EW. Circumcision in the United States: prevalence, prophylactic effects, and sexual practice. JAMA 1997;277:1052–7.PubMedCrossRefGoogle Scholar
  69. 69.
    Laumann EO, Gagnon JH, Michael RT, Michaels S. The Social Organization of Sexuality: Sexual Practices in the United States Chicago: The University of Chicago Press 1994.Google Scholar
  70. 70.
    Wiswell TE. Personal communication. Cited in. Bigelow J. The Joy of Uncircumcising! 2nd ed. Aptos: Hourglass. 1995:3–7.Google Scholar
  71. 71.
    Taylor JR, Lockwood AP, Taylor AJ. The prepuce: specialized mucosa of the penis and its loss to circumcision. Br J Urol 1996;77:291–5.PubMedGoogle Scholar
  72. 72.
    Cold C, Tarara R. Penile and clitoral prepuce mucocutaneous receptors in macaca mulatta. Vet Pathol 1997;34:506.Google Scholar
  73. 73.
    Halata Z, Munger B. The neuroanatomical basis for the protopathic sensibility of the human glans penis. Brain Res 1986;371:205–30.PubMedCrossRefGoogle Scholar
  74. 74.
    Tutin CEG, McGinnis PR. Chimpanzee reproduction in the wild. In: Graham CE, ed. Reproductive Biology of rhe Great Apes. New York: Academic Press. 1981.Google Scholar
  75. 75.
    Goodall, J. The Chimpanzees of Gombe: Pafterns of Behavior. Cambridge, Mass: Belknap. 1986.Google Scholar
  76. 76.
    Pacheco P, Martinez-Gomez M, Whipple B, Beyer C, Komisaruk BR. Somato-motor components of the pelvic and pudendal nerves of the female rat. Brain Res 1989;490:85–94.PubMedCrossRefGoogle Scholar
  77. 77.
    Taylor JR, Lockwood AP, Taylor AJ. The prepuce: specialized mucosa of the penis and its loss to circumcision. BrJ Urol 1996;77:291–5.Google Scholar
  78. 78.
    Nadler RD. Proximate and ultimate influences on the regulation of mating in the great apes. Am J Primatol 1995;37:93–102.CrossRefGoogle Scholar
  79. 79.
    Williams-Ashman HG. Enigmatic features of penile development and functions. Perspectives Biol Med 1990;33:335–74.Google Scholar
  80. 80.
    Dixson AF. Baculum length and copulatory behavior in primates. Am J Primatol 1987;13:51–60.CrossRefGoogle Scholar

Copyright information

© Kluwer Academic / Plenum Publishers, New York 1999

Authors and Affiliations

  • Christopher J. Cold
  • Kenneth A. McGrath

There are no affiliations available

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