Effect of Basic Fibroblast Growth Factor on the Regional Myocardial Blood Flow in Acutely Infarcted Myocardium in Rats
This study showed that intramyocardial injection of basic fibroblast growth factor (bFGF) 100 μg neither enhances angiogenesis nor salvages myocardium in the acutely infarcted myocardium in rats. Although enhanced angiogenesis and myocardial salvage by bFGF has been shown in dogs and pigs, further experimental studies are necessary before applying bFGF in clinical practice.
KeywordsInfarct Size Basic Fibroblast Growth Factor Coronary Occlusion Infarcted Area Native Collateral
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