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Effect of Basic Fibroblast Growth Factor on the Regional Myocardial Blood Flow in Acutely Infarcted Myocardium in Rats

  • Masahiko Inagaki
  • Kinji Ishikawa
  • Iwao Ogawa
  • Akio Kimura
  • Masaru Miyataka
  • Takaya Hasegawa
  • Koji Kitayama
  • Ryo Katori
Part of the Progress in Experimental Cardiology book series (PREC, volume 1)

Abstract

This study showed that intramyocardial injection of basic fibroblast growth factor (bFGF) 100 μg neither enhances angiogenesis nor salvages myocardium in the acutely infarcted myocardium in rats. Although enhanced angiogenesis and myocardial salvage by bFGF has been shown in dogs and pigs, further experimental studies are necessary before applying bFGF in clinical practice.

Keywords

Infarct Size Basic Fibroblast Growth Factor Coronary Occlusion Infarcted Area Native Collateral 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1998

Authors and Affiliations

  • Masahiko Inagaki
    • 1
  • Kinji Ishikawa
    • 1
  • Iwao Ogawa
    • 1
  • Akio Kimura
    • 1
  • Masaru Miyataka
    • 1
  • Takaya Hasegawa
    • 1
  • Koji Kitayama
    • 1
  • Ryo Katori
    • 1
  1. 1.Osaka University Medical SchoolJapan

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