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Methods in Bone Biology pp 127–148Cite as

Methods for studying cell death in bone

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Abstract

Apoptosis is a common form of cell death that controls cell numbers in most tissues during their development as well as in a wide variety of normal and pathological settings. It has been defined by a series of characteristic morphological changes that take place in nuclear chromatin and cytoplasm of cells dying by a mechanism that differs from ischaemic necrosis in that it typically affects single cells, rather than groups of cells [1, 2], These changes appear to be regulated in affected cells; hence the alternative terms: programmed, biological, physiological or controlled cell death.

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Authors
  1. Brendan F. Boyce
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  2. David E. Hughes
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  3. Kenneth R. Wright
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Editors and Affiliations

  1. Department of Anatomy and Developmental Biology, University College London, London, UK

    Timothy R. Arnett

  2. Eastman Dental Institute, University College London, London, UK

    Brian Henderson

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© 1998 Chapman and Hall Ltd

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Boyce, B.F., Hughes, D.E., Wright, K.R. (1998). Methods for studying cell death in bone. In: Arnett, T.R., Henderson, B. (eds) Methods in Bone Biology. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38227-2_5

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  • DOI: https://doi.org/10.1007/978-0-585-38227-2_5

  • Publisher Name: Springer, Boston, MA

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