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Cytokines and biological response modifiers in the treatment of infection

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Book cover Management of Infectious Complications in Cancer Patients

Part of the book series: Cancer Treatment and Research ((CTAR))

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Abstract

Patients undergoing myelosuppressive cancer therapy (chemotherapy or radiation) are at an increased risk to develop potentially life-threatening infections. The incidence appears to be strongly correlated with the duration and degree of absolute neutropenia [1]. A neutrophil count of <500 cells/mm3, and especially of <100 cells/mm3, carries an increased risk for fever and bacterial infections, and a prolonged duration of neutropenia increases the risk for fungal and other infectious complications [26].

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Mueller, B.U., Pizzo, P.A. (1998). Cytokines and biological response modifiers in the treatment of infection. In: Noskin, G.A. (eds) Management of Infectious Complications in Cancer Patients. Cancer Treatment and Research. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38152-7_8

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