Neurohumoral Control of the Vascular System

  • Stéphane Laurent
Part of the Basic Science for the Cardiologist book series (BASC, volume 1)


Through the modification of the neuronal discharge or changes in circulating catecholamines, the autonomic nervous system induces central or local vasomotor alterations and participates in the control of the internal environment and homeostasis. The vascular smooth muscle is the effector organ for these alterations. Indeed, with the exception of capillaries and some venules, the vessels have the ability to alter their calibre, to influence the regional (or total) peripheral resistance and capacitance, and to influence the cardiac output and its distribution. Several studies have demonstrated the extreme diversity of responses of different blood vessels to alteration in autonomic control [1].


Brachial Artery Vasoactive Intestinal Peptide Blood Flow Velocity Large Artery Blood Velocity 
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Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Stéphane Laurent
    • 1
    • 2
  1. 1.Department of PharmacologyBroussais HospitalFrance
  2. 2.INSERM U337ParisFrance

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