Stiffness of Wall Material in Human Hypertension

  • Michel E. Safar
Part of the Basic Science for the Cardiologist book series (BASC, volume 1)


Damage of the large arteries is strongly associated with cardiovascular accidents, mainly in the cerebral, the coronary and the renal circulation [1,2]. Because such accidents are observed both in normotensive and hypertensive populations, it has been suggested that a common trigger factor, atherosclerosis, plays a major contributive role in the mechanism of the vascular alterations. However, independently of atherosclerosis, hypertensive vessels are thicker and stiffer than those of corresponding normotensive controls [2, 3, 4]. Thus the question is raised to know whether the specific alterations of hypertensive vessels play a role in cardiovascular morbidity and mortality.


Arterial Wall Pulse Wave Velocity Radial Artery Wall Material Systolic Hypertension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Michel E. Safar
    • 1
  1. 1.Department of Internal medecine and INSERM U337Broussais HospitalParisFrance

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