Male Senescence

  • J. L. Tenover
Part of the Mineralogical Society Series book series (ENDO, volume 5)


There is no “andropause” that corresponds to the female menopause, but normal aging in men is accompanied by a gradual decline in serum levels of testosterone and changes in the hypothalamic-pituitary-gonadal axis. Although there is a great deal of variability among individuals in this regard, and the process can be impacted by disease and medications, there has been a growing interest over the past decade in whether declining testosterone levels result in a significant number of older men becoming hypogonadal and whether replacement therapy might be beneficial. It is the purpose of this chapter to review the changes that occur with normal aging in the male reproductive axis and to discuss the issues that surround androgen replacement therapy in the older man.


Luteinizing Hormone Testosterone Level Male Senescence Serum Testosterone Level Testosterone Replacement 
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© Kluwer Academic Publishers 1999

Authors and Affiliations

  • J. L. Tenover
    • 1
  1. 1.Emory University School of MedicineAtlanta

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