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Paracrine Control of Testis Function

  • Chapter
Male Reproductive Function

Part of the book series: Mineralogical Society Series ((ENDO,volume 5))

Abstract

Two concepts have been put forward to explain the regulation of testicular function. Firstly, it has been suggested that testicular function is regulated primarily by pituitary gonadotropins (endocrine regulation). Secondly, it has been proposed that the “testis is not a mass of independently developing cells” (Roosen-Runge, 1952), so there are presumably local regulatory mechanisms to coordinate the activities of testicular cells (paracrine regulation). It is now generally accepted that there is no conflict between the concepts of peripheral control of testicular function and intratesticular control. The integration of these two concepts accounts for gonadotrophins regulating testicular paracrine activities and some paracrine factors regulating the testicular effects of pituitary hormone and exerting endocrine control over pituitary function.

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Authors and Affiliations

  1. INSERM, University of Rennes, Rennes Cedex, France

    B. Jégou, C. Pineau & A. Dupaix

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  1. B. Jégou
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  2. C. Pineau
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  3. A. Dupaix
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  1. Harbor-UCLA Medical Center, Torrance, California, USA

    Christina Wang M.D.

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© 1999 Kluwer Academic Publishers

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Jégou, B., Pineau, C., Dupaix, A. (1999). Paracrine Control of Testis Function. In: Wang, C. (eds) Male Reproductive Function. Mineralogical Society Series, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38145-9_3

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  • DOI: https://doi.org/10.1007/978-0-585-38145-9_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-8520-2

  • Online ISBN: 978-0-585-38145-9

  • eBook Packages: Springer Book Archive

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