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Cardiac myocytes

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Apoptosis in Cardiac Biology

Part of the book series: Basic Science for the Cardiologist ((BASC,volume 5))

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Abstract

In recent years myocyte loss due to apoptosis has gained increasing attention in the field of cardiovascular research, as myocyte apoptosis was observed in several disease states suggesting a potential pathophysiological role. Whereas initial studies were mostly observational verifying the occurrence of apoptotic myocytes in the heart, increasingly efforts are being made to disentagle the intracellular mechanisms that induce or inhibit myocyte apoptosis. As other chapters of this book deal with the more general aspects of apoptosis, the scope of this article will be limited to summarize current knowledge of the role of apoptosis in myocardial disease and the regulatory mechanisms known to be involved in myocyte apoptosis.

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Authors and Affiliations

  1. Universität Heidelberg, Heidelberg, Germany

    Armin Haunstetter M.D., Markus Haass M.D. & Seigo Izumo M.D.

  2. Harvard Medical School, Boston, MA, USA

    Armin Haunstetter M.D., Markus Haass M.D. & Seigo Izumo M.D.

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  1. University of Regensburg, Germany

    Heribert Schunkert  & G. A. J. Riegger  & 

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Haunstetter, A., Haass, M., Izumo, S. (2000). Cardiac myocytes. In: Schunkert, H., Riegger, G.A.J. (eds) Apoptosis in Cardiac Biology. Basic Science for the Cardiologist, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38143-5_12

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  • DOI: https://doi.org/10.1007/978-0-585-38143-5_12

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