Abstract
In recent years myocyte loss due to apoptosis has gained increasing attention in the field of cardiovascular research, as myocyte apoptosis was observed in several disease states suggesting a potential pathophysiological role. Whereas initial studies were mostly observational verifying the occurrence of apoptotic myocytes in the heart, increasingly efforts are being made to disentagle the intracellular mechanisms that induce or inhibit myocyte apoptosis. As other chapters of this book deal with the more general aspects of apoptosis, the scope of this article will be limited to summarize current knowledge of the role of apoptosis in myocardial disease and the regulatory mechanisms known to be involved in myocyte apoptosis.
Keywords
- Cardiac Myocytes
- Atrial Natriuretic Peptide
- Ventricular Myocytes
- Myocyte Apoptosis
- Cardiac Myocyte Apoptosis
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Haunstetter, A., Haass, M., Izumo, S. (2000). Cardiac myocytes. In: Schunkert, H., Riegger, G.A.J. (eds) Apoptosis in Cardiac Biology. Basic Science for the Cardiologist, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38143-5_12
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