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Apoptosis and cell cycle in endothelial cells

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Apoptosis in Cardiac Biology

Part of the book series: Basic Science for the Cardiologist ((BASC,volume 5))

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Abstract

Apoptosis is an active process of cell death that occurs both under physiologic and pathophysiologic conditions. Specifically, apoptosis has been involved in vasculogenesis and atherosclerosis, inflammation, as well as wound healing, respectively. Its hallmark is the cleavage of genomic DNA into nucleosomal fragments of 180 bp (1). Although it has not been established to what extent endothelial cell death occurs in vivo, there is increasing evidence that endothelium may become apoptotic in various disease states.

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  1. Universität Tübingen, Tübingen, Germany

    Ioakim Spyridopoulos M.D.

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Spyridopoulos, I. (2000). Apoptosis and cell cycle in endothelial cells. In: Schunkert, H., Riegger, G.A.J. (eds) Apoptosis in Cardiac Biology. Basic Science for the Cardiologist, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38143-5_10

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  • DOI: https://doi.org/10.1007/978-0-585-38143-5_10

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