Advertisement

The fate of second kidney transplant after recurrence of glomerulonephritis in the first transplant

  • Martine De Meyer
  • Claire Pouteil-Noble
  • Jacques Peeters
  • Jean-Pierre Cosyns
  • Brigitte McGregor
  • Yves Vanrenterghem
  • Jean-Louis Touraine
  • Jean-Paul Squifflet
  • Yves Pirson
Part of the Transplantation and Clinical Immunology book series (TRAC, volume 29)

Abstract

Though recurrent primary glomerulonephritis (PG) currently accounts for only less than 2% of all graft failures in the adult [1, 2, 3, 4], this rate is expected to increase with both the improvement of patient and graft survivals and the ineffectiveness of most attempts at recurrence treatment. The patient who has lost a first graft to PG recurrence expectedly wishes proper information on the risk of recurrence in a further graft. Except for focal glomerulosclerosis (FGS) [5, 6, 7], there is very scarce data on this issue in the literature. We thus decided to review our experience with the fate of a second transplant in patients who had recurrence of PG in their first transplant.

Keywords

Nephrotic Syndrome Membranous Nephropathy Focal Segmental Glomerulosclerosis Membranoproliferative Glomerulonephritis Native Kidney 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Cameron JS. Recurrent disease in renal allografts. Kidney Int. 1993; 44(Suppl. 43): 91–94.Google Scholar
  2. 2.
    Ramos EL, Tisher CC. Recurrent disease in the kidney transplant. Am. J. Kidney Dis. 1994; 24: 142–154.PubMedGoogle Scholar
  3. 3.
    Davison AM. Renal transplantation: recurrence of original disease with particular reference to primary glomerulonephritis. Nephrol. Dial. Transplant. 1995; 10(Suppl. 1): 81–84.PubMedGoogle Scholar
  4. 4.
    Michielsen M. Recurrence of the original disease. Does this influence renal graft failure? Kidney Int. 1995: 48(Suppl. 52): 79–84.Google Scholar
  5. 5.
    Artero M., Biava C, Amend W, Tomlanovich S, Vincenti F. Recurrent focal glomerulosclerosis; natural history and response to therapy. Am. J. Med. 1992; 92: 375–383.PubMedCrossRefGoogle Scholar
  6. 6.
    Stephanian E, Matas AJ, Mauer SM, Chavers B, Nevins T, Kashtan C, Sutherland DER, Gores P, Najarian JS. Recurrence of disease in patients retransplanted for focal segmental glomerulosclerosis. Transplantation 1992; 53: 755–757.PubMedCrossRefGoogle Scholar
  7. 7.
    Dantal J, Soulillou JP. Récidive des hyalinoses segmentaires et focales après transplantation rénale. In: Funck-Brentano JL, Bach JF, Kreis L, Grünfeld JP (ed.). Act. Néphrol Hôp. Necker.: Flammarion Médecine-Sciences, Paris, 1995: 91–106.Google Scholar
  8. 8.
    Odorico JS, Knechtle SJ, Rayhill SC, Pirsch JD, D’Alessandro AM, Beizer FO, Sollinger HW. The influence of native nephrectomy on the incidence of recurrent disease following renal transplantation for primary glomerulonephritis. Transplantation 1996; 61: 228–234.PubMedCrossRefGoogle Scholar
  9. 9.
    Tejani A, Stablein DH. Recurrence of focal segmental glomerulosclerosis posttransplantation: a special report of the North American Pediatric Renal Transplant Cooperative Study. J. Am. Soc. Nephrol. 1992; 2(Suppl. 3): 258–263.Google Scholar
  10. 10.
    Banfi G, Colturi C, Montagnino G, Ponticelli C. The recurrence of focal segmental glomerulosclerosis in kidney transplant patients treated with cyclosporine. Transplantation 1990; 50: 594–596.PubMedCrossRefGoogle Scholar
  11. 11.
    Pouteil-Noble C, Colon S, Donia-Maged A, Cochat P, Lacavalerie B, Touraine JL. Influence of cyclosporine A on the recurrence of focal segmental glomerulosclerosis after renal transplantation. XIIIth International Congress of Nephrology, Jerusalem, June 13–18, 1993, p. 31.Google Scholar
  12. 12.
    Ingulli E, Tejani A, Butt KMH, Rajpoot D, Gonzalez R, Pomrantz A, Ettenger R. High-dose cyclosporine therapy in recurrent nephrotic syndrome following renal transplantation. Transplantation 1990; 49: 219–221.PubMedCrossRefGoogle Scholar
  13. 13.
    Ranchin B, Gagnadoux MF, Broyer M et al. Intérêt de la ciclosporine dans le traitement des récidives de néphrose après transplantation rénale. Néphrologie 1996; 17: 441–445.PubMedGoogle Scholar
  14. 14.
    McCauley J, Tzakis AG, Fung JJ, Todo S, Starzl TE. FK506 in steroid-resistant focal sclerosing glomerulonephritis of childhood. Lancet 1990; 335: 674.PubMedCrossRefGoogle Scholar
  15. 15.
    Cochat P, Schell M, Ranchin B, Boueva A, Saïd MH. Management of recurrent nephrotic syndrome after kidney transplantation in children. Clin. Nephrol. 1996; 46: 17–20.PubMedGoogle Scholar
  16. 16.
    Savin VJ, Sharma R, Sharma M et al. Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis. N. Engl. J. Med. 1996; 334: 878–883.PubMedCrossRefGoogle Scholar
  17. 17.
    McCoy R, Clapp J, Seigler HF. Membranoproliferative glomerulonephritis. Am. J. Med. 1975; 59: 288–292.PubMedCrossRefGoogle Scholar
  18. 18.
    Habib R, Broyer M. Clinical significance of allograft glomerulopathy. Kidney Int. 1993; 44(Suppl. 43): 95–98.Google Scholar
  19. 19.
    Glicklich D, Matas AJ, Sablay LB et al. Recurrrent membranoproliferative glomerulonephritis type 1 in successive renal transplants. Am. J. Nephrol. 1987; 7: 143–149.PubMedGoogle Scholar
  20. 20.
    Muczynski KA. Plasmapheresis maintained renal function in an allograft with recurrent membranoproliferative glomerulonephritis type I. Am. J. Nephrol. 1995; 15: 446–449.PubMedGoogle Scholar
  21. 21.
    Davison AM, Johnston PA. Allograft membranous nephropathy. Nephrol. Dial. Transplant. 1992; (Suppl. 1): 114–118.Google Scholar
  22. 22.
    Couchoud C, Pouteil-Noble C, Colon S, Touraine JL. Recurrence of membranous nephropathy after renal transplantation. Transplantation 1995; 59: 1275–1279.PubMedGoogle Scholar
  23. 23.
    Cosyns JP, Pirson Y, Squifflet JP, van Ypersele de Strihou C. Post-transplant recurrence of membranous nephropathy: prevalence and outcome. XIIIth International Congress of Nephrology, Jerusalem, June 13–18, 1993, p. 142.Google Scholar
  24. 24.
    Cosyns JP, Pirson Y, Squifflet JP et al. De novo membranous nephropathy in human renal allografts: report of nine patients. Kidney Int. 1982; 59: 177–183.CrossRefGoogle Scholar
  25. 25.
    Innes A, Woodrow G, Boyd SM, Beckingham IJ, Morgan AG. Recurrent membranous nephropathy in successive renal transplants. Nephrol. Dial. Transplant. 1994; 9: 323–325.PubMedGoogle Scholar
  26. 26.
    Josephson MA, Spargo B, Hollandsworth D, Thistlethwaite JR. The recurrence of recurrent membranous glomerulopathy in a renal transplant recipient: case report and literature review. Am. J. Kidney Dis. 1994; 24: 873–878.PubMedGoogle Scholar
  27. 27.
    Odum J, Peh CA, Clarkson AR et al. Recurrent mesangial IgA nephritis following renal transplantation. Nephrol. Dial. Transplant. 1994; 9: 309–312.PubMedGoogle Scholar
  28. 28.
    Kessler M, Hiesse C, Hestin D, Mayeux D, Boubenider K, Charpentier B. Recurrence of immunoglobulin A nephropathy after renal transplantation in the cyclosporine era. Am. J. Kidney Dis. 1996; 28: 99–104.PubMedGoogle Scholar
  29. 29.
    Frohnert PP, Donadio JV, Velosa JA, Holley KE, Sterioff S. The fate of renal transplants in patients with IgA nephropathy. Clin. Transplantation 1997; 11: 127–133.Google Scholar
  30. 30.
    Diaz-Tejeiro R, Maduell F, Diez J et al. Loss of renal graft due to recurrent IgA nephropathy with rapidly progressive course: an unusual clinical evolution. Nephron 1990; 54: 341–343.PubMedCrossRefGoogle Scholar
  31. 31.
    Streather CP, Scoble JE. Recurrent IgA nephropathy in a renal allograft presenting as crescentic glomerulonephritis. Nephron 1994; 66: 113–114.PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1997

Authors and Affiliations

  • Martine De Meyer
  • Claire Pouteil-Noble
  • Jacques Peeters
  • Jean-Pierre Cosyns
  • Brigitte McGregor
  • Yves Vanrenterghem
  • Jean-Louis Touraine
  • Jean-Paul Squifflet
  • Yves Pirson

There are no affiliations available

Personalised recommendations