Kidney Retransplantation in Sensitized Patients: Experience with a New Immunosuppressive Protocol
The results of retransplantation in those patients with high panel reactive antibodies (PRA) are worse than in other recipients. Nevertheless the number of retransplantations and the number of sensitized patients on the waiting list are increasing. To improve the results we used a new immunosuppressive strategy with a single shot of intraoperative ATG followed by a high dose mycophenolate mofetil maintenance immunosuppression. The working mechanism of mycophenolate mofetil with lymphocyte suppression is likely to improve the results in those patients, especially in conjunction with an intraoperative ATG bolus.