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Kidney Retransplantation in Sensitized Patients: Experience with a New Immunosuppressive Protocol

  • J. V. Woellwarth
  • M. Behrend
  • H. J. Schlitt
  • K. J. Oldhafer
  • B. Nashan
  • V. Kliem
  • R. Brunkhorst
  • R. Pichlmayr
Part of the Transplantation and Clinical Immunology book series (TRAC, volume 29)

Abstract

The results of retransplantation in those patients with high panel reactive antibodies (PRA) are worse than in other recipients. Nevertheless the number of retransplantations and the number of sensitized patients on the waiting list are increasing. To improve the results we used a new immunosuppressive strategy with a single shot of intraoperative ATG followed by a high dose mycophenolate mofetil maintenance immunosuppression. The working mechanism of mycophenolate mofetil with lymphocyte suppression is likely to improve the results in those patients, especially in conjunction with an intraoperative ATG bolus.

Keywords

Mycophenolate Mofetil Single Shot Maintenance Immunosuppression Immunosuppressive Protocol Panel Reactive Antibody 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Kluwer Academic Publishers 1997

Authors and Affiliations

  • J. V. Woellwarth
    • 1
  • M. Behrend
    • 1
  • H. J. Schlitt
    • 1
  • K. J. Oldhafer
    • 1
  • B. Nashan
    • 1
  • V. Kliem
    • 1
  • R. Brunkhorst
    • 1
  • R. Pichlmayr
    • 1
  1. 1.Abteilung für Abdominal- und Transplantationschirurgie, Klinik für NephrologieMedizinische Hochschule HannoverHannoverGermany

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