Regulation of Inflammation by Fas Ligand Expression on the Vascular Endothelium

  • Kenneth Walsh
  • Masataka Sata
Part of the Basic Science for the Cardiologist book series (BASC, volume 2)


The monolayer of endothelial cells that coat the luminal surface of the vessel wall have numerous physiological functions including the prevention of coagulation, control of vascular permeability, maintenance of vascular tone, and regulation of leukocyte extravasation. While the vascular endothelium plays a pivotal role in recruiting inflammatory cells at the site of infection or wounding, the normal endothelium is believed to serve as a barrier to inflammation in the absence of inflammatory stimuli.


Vascular Smooth Muscle Cell Proliferation Subendothelial Space Leukocyte Extravasation Molecular Cardiology 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Kenneth Walsh
    • 1
  • Masataka Sata
    • 1
  1. 1.Tufts University and St. Elizabeth’s Medical CenterUSA

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