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Molecular Mechanisms of Myocardial Remodeling

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Book cover Molecular Cardiology in Clinical Practice

Part of the book series: Basic Science for the Cardiologist ((BASC,volume 2))

Abstract

Myocardial dysfunction is a progressive condition. Early after an insult to the myocardium (e.g., myocardial infarction) there may be little or no immediate reduction in overall pump function, particularly if the damage has been mild. However, with time there is a relentless deterioration in both the structure and function of the ventricle by a process referred to as “remodeling” (1). The specific features of the remodeling process depend, to a large extent, on the nature of the underlying stimulus.

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  1. Boston University School of Medicine, USA

    Wilson S. Colucci M.D.

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  1. Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, USA

    Michael Sanders  & John B. Kostis  & 

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Colucci, W.S. (1999). Molecular Mechanisms of Myocardial Remodeling. In: Sanders, M., Kostis, J.B. (eds) Molecular Cardiology in Clinical Practice. Basic Science for the Cardiologist, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38141-1_2

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  • DOI: https://doi.org/10.1007/978-0-585-38141-1_2

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