Management of the Late Menopause: Ultra Low-Dose Adjustive Estrogen Therapy

  • Morris Notelovitz
Part of the Medical Science Symposia Series book series (MSSS, volume 13)


Women over 65 years of age do benefit from hormone therapy, but compliance is often poor because of estrogen-induced side effects and fear of breast cancer. Ultra low-dose estrogen therapy (ULET), adjusted to the need of the individual is effective in meeting various therapeutic goals while minimizing unacceptable side effects. The four main principles of ULET include: individualizing therapy by patient examination and selective testing; prescription of the lowest effective dose of a natural estrogen; choosing the route of administration based on the patient’s preference and medical need; adjusting the therapy over time by monitoring symptomatic and specific biologic end-point responses.


Bone Mineral Density Estrogen Therapy Endometrial Hyperplasia Lower Effective Dose Unacceptable Side Effect 
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Copyright information

© Kluwer Academic Publishers and Fondazione Giovanni Lorenzini 1999

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  • Morris Notelovitz

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