Advertisement

Part B: Outcomes With ESRD Therapy: A Critical Overview from The United States

  • Friedrich K. Port
  • Marc N. Turenne
  • Philip J. Held

Abstract

Patient survival is a very basic but important outcome of any therapeutic intervention. In the case of end stage renal disease (ESRD), outcome studies have included several other outcomes such as quality of life indicators, morbidity measures (e.g., hospitalizations), length of time on a treatment modality (‘technique survival’) and survival with a functioning kidney allograft (graft survival). The establishment of regional and national registries has markedly facilitated the evaluation of these outcomes in actual practice rather than in the referral practice or related multicenter environment. This chapter will focus primarily on population-based patient survival studies using information from the United States Renal Data System (USRDS) and the Michigan Kidney Registry

Keywords

Dialysis Patient Hemodialysis Patient United States Renal Data System High Acceptance Rate Relative Mortality Risk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457, 1972CrossRefGoogle Scholar
  2. 2.
    Cox D: Regression models and life tables. J R Stat Soc 34: 187, 1972Google Scholar
  3. 3.
    United States Renal Data System: USRDS 1995 Annual Data Report. National Institutes of Health, National Institutes of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 1995, and Am J Kidney Dis 26 (Suppl 2): S1, 1995Google Scholar
  4. 4.
    Held PJ, Carroll CE, Liska DW, Turenne MN, Port FK: Hemodialysis therapy in the US: what is the dose and does it matter? Am J Kidney Dis 24: 974, 1994PubMedGoogle Scholar
  5. 5.
    Tokars JI, Alter MJ, Favero MS, Moyer LA, Bland LA: National surveillance of dialysis-associated diseases in the United States. ASAIO Trans 39: 71, 1993CrossRefGoogle Scholar
  6. 6.
    Kjellstrand CM, Hylander B, Collins AC: Mortality on dialysis — on the influence of early start, patient characteristics, and transplantation and acceptance rates. Am J Kidney Dis 15: 483, 1990PubMedGoogle Scholar
  7. 7.
    Held PJ, Akiba T, Stearns NS et al.: Survival of middle aged dialysis patients in Japan and the US. in Death on Dialysis: Preventable or Inevitable, edited by Friedman EA, Dordrecht/Boston/London, Kluwer Academic Publishers, 1994, p 13Google Scholar
  8. 8.
    Held PJ, Brunner F, Odaka M, Garcia JR, Port FK, Gaylin DS: Five-year survival for end-stage renal disease patients in the United States, Europe, and Japan, 1982 to 1987. Am J Kidney Dis 15: 451, 1990PubMedGoogle Scholar
  9. 9.
    Port FK, Wolfe RA, Mauger EA, Berling DP, Jiang K: Comparison of survival probabilities for dialysis patients versus cadaveric renal transplant recipients. JAMA 270: 1339, 1993PubMedCrossRefGoogle Scholar
  10. 10.
    Nelson CB, Port FK, Wolfe RA, Guire KE: Comparison of CAPD and hemodialysis patient survival with evaluation of trends during the 1980s. J Am Soc Nephrol 3: 1147, 1992PubMedGoogle Scholar
  11. 11.
    Port FK, Nelson CB, Wolfe RA: Mortality comparison for diabetic ESRD patients treated with CAPD versus hemodialysis. in Death on Dialysis: Preventable or Inevitable, edited by Friedman EA, Dordrecht/ Boston/London, Kluwer Adademic Publishers, 1994, p 113Google Scholar
  12. 12.
    Held PJ, Port FK, Turenne MN, Gaylin DS, Hamburger RJ, Wolfe RA: Continuous ambulatory peritoneal dialysis and hemodialysis: comparison of patient mortality with adjustment for comorbid conditions. Kidney Int 45: 1163, 1994PubMedCrossRefGoogle Scholar
  13. 13.
    United States Renal Data System: Patient selection to peritoneal dialysis versus hemodialysis according to comorbid conditions. Am J Kidney Dis 20: 20, 1992Google Scholar
  14. 14.
    Held PJ, Blagg CR, Liska DW, Port FK, Hakim R, Levin NW: The dose of hemodialysis according to dialysis prescription in Europe and in the United States. Kidney Int 42(Suppl 38): S16, 1992Google Scholar
  15. 15.
    Owens WF, Lew NL, Yan Liu SM, Lowrie EG, Lazarus JM: The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med 329: 1101, 1993Google Scholar

Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Friedrich K. Port
    • 1
  • Marc N. Turenne
    • 2
  • Philip J. Held
    • 3
  1. 1.Kidney Epidemiology and Cost CenterUniversity of MichiganAnn ArborUSA
  2. 2.Department of Medicine and EpidemiologyUniversity of MichiganAnn ArborUSA
  3. 3.Department of Health Services Management and PolicyUniversity of MichiganAnn ArborUSA

Personalised recommendations