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Continuous Arteriovenous Hemofiltration and Related Therapies

  • Andre A. Kaplan

Abstract

By the late seventies, machine driven hemofiltration had been investigated as a treatment for chronic uremia (1, 2, 3, 4). With the operational characteristics and advantages of convective based solute removal well described, the availability of low resistance hemofilters allowed for the development of filtration techniques which could be powered by the patient’s arterial blood pressure. In 1977, Kramer et al. first proposed arteriovenous hemofiltration as a method of emergency fluid removal in patients resistant to diuretics (5). In 1979, Neff and colleagues used the technique for outpatient control of uremia (6). In 1980, Paganini and Nakamoto employed spontaneous filtration to maintain fluid balance in patients with acute renal failure (7) and Shaldon et al. described its use as an adjunct to chronic hemodialysis (8). Finally, in a follow up to their original work, Kramer et al. demonstrated that continuous arteriovenous hemofiltration could be used to supplant conventional dialytic techniques in the intensive care unit (9, 10).

Keywords

Acute Renal Failure Transmembrane Pressure Fluid Removal Nafamostat Mesilate Ultrafiltration Rate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Andre A. Kaplan
    • 1
  1. 1.Division of NephrologyUniversity of CT Health CenterFarmingtonUSA

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