Dynamic Cardiomyoplasty: Multicenter Clinical Trials

  • B. D. Mott
  • L. L. Austin
  • R. C. -J. Chiu


Patients with chronic heart failure suffer from variable degrees of abnormal cardiac performance reflected in their exercise intolerance, fatigue, and dyspnea. It is estimated that approximately 400 000 people develop heart failure each year in the United States, adding to the nearly 3 million patients already suffering from this syndrome[1]. Patients with mild to moderate severity of disease can usually be managed medically with today’s arsenal of drugs, including angiotensin-converting enzyme (ACE) inhibitors, diuretics, and inotropes. Furthermore, patients with correctable valvular or coronary lesions increasingly can be managed by standard cardiac surgery. Despite this, mortality in this population remains extremely high. The overall 1-year and 5-year survival rates are 57% and 25% for men, respectively, with slightly better rates seen in women[2].


Leave Ventricular Ejection Fraction Pulmonary Vascular Resistance Artificial Heart Latissimus Dorsi Muscle Reference Patient 
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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • B. D. Mott
  • L. L. Austin
  • R. C. -J. Chiu

There are no affiliations available

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