Xenotransplantation of the Heart

  • D. K. C. Cooper


It is generally accepted that there is a shortage of suitable human organs for purposes of transplantation[1]. The total number of patients on the United Network for Organ Sharing (UNOS) waiting list in the USA is now in excess of 45 000, over double the number registered in 1988. Over 3000 patients are awaiting a heart transplant. These data indicate that the demand for organs in the USA is increasing by about 10–15% each year. Worldwide, this number can be increased by at least a further 50%, and possibly 100%. Furthermore, the median waiting period for several types of donor organ has increased significantly in recent years. In particular, patients in need of a liver or heart wait approximately twice as long today as they did 5 years ago.


Transplant Proc Hyperacute Rejection Total Lymphoid Irradiation Xenograft Rejection Vascular Rejection 
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© Kluwer Academic Publishers 1996

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  • D. K. C. Cooper

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