Early Clinical Experience with Permanent Cardiac Replacement by a Mechanical Device

  • D. K. C. Cooper


Cooley (Figure 1) and colleagues’ implanted the first total artificial heart (TAH) in a human in 1969. This attempt was intended as an interim measure until a suitable human heart could be located and transplanted. This group performed a second bridge-to-transplant procedure in 1981[2],[3]. Since then the TAH has successfully served as a bridge to transplant in many patients.


Cardiac Output Artificial Heart Subacute Bacterial Endocarditis Diagnostic Unit Plasma Free Hemoglobin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Cooley DA, Liotta D, Hallman GL et al. Orthotopic cardiac prosthesis for two-staged cardiac replaccment. Am J Cardiol. 1969;24:723.PubMedCrossRefGoogle Scholar
  2. 2.
    Frazier OH, Akutsu T, Cooley DA. Total artificial heart (TAH) utilization in man. Trans Am Soc Artif Intern Organs. 1982;23:534.Google Scholar
  3. 3.
    Cooley DA. Staged cardiac transplantation: Report of three cases. Heart Transplant. 1982;1:145.Google Scholar
  4. 4.
    De Vries WC, Anderson JL, Joyce LDet al. Clinical use of the total artificial heart. N Engl J Med. 1984;310:273.CrossRefGoogle Scholar
  5. 5.
    Joyce LD, De Vries WC, Hastings WL et al. Response of the human body to the first permanent implant of the Jarvik-7 total artificial heart. Trans Am Soc Artif Intern Organs. 1983;29:81.PubMedGoogle Scholar
  6. 6.
    Anderson FL, De Vries WC, Anderson JL, Joyce LD. Evaluation of total artificial heart performance in man. Am J Cardiol. 1984;54:394.PubMedCrossRefGoogle Scholar
  7. 7.
    De Vries WC, Joyce LD. The artificial heart. Clin Symp. 1983;35:1.Google Scholar
  8. 8.
    De Vries WC. The permanent artificial heart. Four case reports. J Am Med Assoc. 1988;259:849.CrossRefGoogle Scholar
  9. 9.
    De Vries WC. Surgical technique for implantation of the Jarvik-7-100 total artificial heart. J Am Mod Assoc. 1988;1259:875.CrossRefGoogle Scholar
  10. 10.
    Willshaw P, Nielsen SD, Nannasv H, Pichel R, Olsen DB. A cardiac output monitor and diagnostic unit for pneumatically driven artificial heart. Artif Organs. 1984;8:215.PubMedCrossRefGoogle Scholar
  11. 11.
    Mays JB, Williams MA, Barker LE, Hastings L, De Vries WC. Diagnostic monitoring and drive system management of patients with total artificial heart. Heart Lung. 1986;15:466.PubMedGoogle Scholar
  12. 12.
    Mays JB, Williams MA, Barker LEet al. Clinical management of total artificial heart drive systems. J Am Med Assoc. 1988;259:881.CrossRefGoogle Scholar
  13. 13.
    Levinson MM, Copcland JG, Smith RGet al. Indexes of hemolysis in human recipients of the Jarvik-7 total artificial heart: a cooperative report of 15 patients. J Heart Transplant. 1986;5:236.PubMedGoogle Scholar
  14. 14.
    Joyce LD, Johnson KF, Pierce WS et al. Summary of the world experience with clinical use of total artilicial hearts as heart supporl devices. J Hearl Transplant. 1986;3:229.Google Scholar
  15. 15.
    Kunin CM, Dobbins JJ. Melo JC et al. Infectious complications in four long-term recipients of the Jarvik-7 artificial heart. J Am Med Assoc. 1988;259 860.CrossRefGoogle Scholar
  16. 16.
    Dobbins JJ, Johnson GS, Kunin CM, De Vries WC. Postmortem microbiological findings of two total artificial heart recipients. J Am Med Assoc. 1988;259:865.CrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • D. K. C. Cooper

There are no affiliations available

Personalised recommendations