Abstract
It is likely that organ size is a more important issue in lung transplantation than in transplantation of any other solid organ. Lungs must fit within the confines of the thoracic cage. This space has the capacity to change its size and shape with time; indeed, the very act of ventilation changes the volume of the thorax substantially by the amount of forced vital capacity. Because lungs are easily distensible, they have the ability to change their size and shape, and can frequently fill the space made available to them. In fact, the safe limits with respect to size mismatching between donors and recipients have not yet been established for lung transplantation.
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References
Knudson RJ, Lebowitz MD, Holberg CJ, Burrows B. Changes in the normal maximal expiratory flow-volume curve with growth and aging. Am Rev Respir Dis. 1983;127:725–34.
Goldman HI, Becklake MR. Respiratory function tests: normal values at median altitudes and the prediction of normal results. Am Rev Tuberc. 1959;79:457–67.
Egan TM, Thompson JT, Detterbeck FC et al. Effect of size (mis)matching in clinical double lung transplantation. Transplantation. 1995;59:707–13.
Starnes VA, Barr ML, Cohen RG. Lobar transplantation: indications, technique, and outcome. J Thorac Cardiovasc Surg. 1994;108:403–11.
Lloyd KS, Barnard P, Holland VA, Noon GP, Lawrence EC. Pulmonary function after heart-lung transplantation using larger donor organs. Am Rev Respir Dis. 1990;142:1026–9.
Stames VA, Barr ML, Cohen FA, Schenkel FA. Barbers RG and the USC Transplant Group. Bilateral living-related lobar transplantation for cystic fibrosis: initial experience. J Heart Lung Transplant. 1994;13(Suppl.):S57 (abstract).
Egan TM, Kaiser LR, Cooper JD. Lung transplantation. Cuit Probl Surg. 1989;26:675–751.
Otulana BA, Mist BA. Scott JP, Wallwork J, Higenbottam T. The effect of recipient lung size on lung physiology after heart-lung transplantation. Transplantation. 1989;48:625–9.
Miyoshi S, Schaefers H-J, Trulock EP et al. Donor selection for single and double lung transplantation: chest size matching and other factors influencing posttransplantation vital capacity. Chest. 1990;98:308–13.
Massard G, Badier M, Guillot C et al. and the Joint Marseille-Montreal Lung Transplant Program. Lung size matching for double lung transplantation based on the submammary thoracic perimeter: accuracy and functional results. J Thorac Cardiovasc Surg. 1993;105:9–14.
Crombleholme TM, Adzick NS, Hardy K et al. Pulmonary lobar transplantation in neonatal swine: a model for treatment of congenital diaphragmatic hernia. S Pediatr Surg. 1990;25:11–18.
Crombleholme TM, Adzick NS, Longaker MT et al. Reduced-size lung transplantation in neonatal swine: technique and short-term physiological response. Ann Thorac Surg. 1990;49:55–60.
Kern JA, Tribble CG, Chan BBK, Flanagan TL, Kron IL. Reduced-size porcine lung transplantation: long-term studies of pulmonary vascular resistance. Ann Thorac Surg. 1992;53:583–9.
Kern JA, Tribble CG, Flanagan TL et al. Growth potential of porcine reduced-size mature pulmonary lobar transplants. J Thorac Cardiovasc Surg. 1992;104:1329–32.
Rannels DE, Russo LA. Compensatory growth. In: Crystal RG, West JB, editors. The lung: scientific foundations, Vol. I. New York: Raven Press; 1991;699–709.
Burri PH. Postnatal development and growth. In: Crystal RG, West JB, editors. The lung: scientific foundations, Vol. I. New York: Raven Press; 1991:677–87.
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© 1996 Kluwer Academic Publishers
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Egan, T.M. (1996). Lung Size and Impact on Transplantation. In: Cooper, D.K.C., Miller, L.W., Patterson, G.A. (eds) The Transplantation and Replacement of Thoracic Organs. Springer, Dordrecht. https://doi.org/10.1007/978-0-585-34287-0_51
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DOI: https://doi.org/10.1007/978-0-585-34287-0_51
Publisher Name: Springer, Dordrecht
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