Lung Size and Impact on Transplantation
It is likely that organ size is a more important issue in lung transplantation than in transplantation of any other solid organ. Lungs must fit within the confines of the thoracic cage. This space has the capacity to change its size and shape with time; indeed, the very act of ventilation changes the volume of the thorax substantially by the amount of forced vital capacity. Because lungs are easily distensible, they have the ability to change their size and shape, and can frequently fill the space made available to them. In fact, the safe limits with respect to size mismatching between donors and recipients have not yet been established for lung transplantation.
KeywordsCystic Fibrosis Forced Vital Capacity Lung Transplant Total Lung Capacity Lung Transplant Recipient
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