Selection and Evaluation of the Potential Thoracic Organ Transplant Recipient - General Considerations
Selection of appropriate recipients for heart or lung transplantation may be the most important factor determining long-term survival, yet selection remains difficult and guidelines vary to some extent from one institution to another–. With increasing experience and success, there has been a relaxation in selection criteria in heart transplant candidates, with both older and younger patients and insulin-requiring diabetics now being offered transplantation. Similarly, with increasing experience in lung transplantation, selection criteria are gradually being modified. Greater experience with the new immunosuppressive regimens that are steadily becoming available, including tacrolimus (FK506) and mycophenolate mofetil, is likely to further broaden the criteria for transplantation.
KeywordsCystic Fibrosis Heart Transplant Donor Organ Lung Transplantation Primary Pulmonary Hypertension
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- 6.Oyer PE, Stinson EB, Bieber CP, Shumway NE. Cardiac transplantation. In Chatterjee, SN, editor. Organ transplantation. Boston: P.S.G. Wright: 1982;347.Google Scholar
- 8.Thompson ME. Selection of candidates for cardiac transplantation. J Heart Transplant. 1983;3:65.Google Scholar
- 9.Cooper DKC, Lanza RP, Boyd ST, Barnard CN. Factors influencing survival following heart transplantation. J Heart Transplant. 1983;3:86.Google Scholar
- 10.Copeland JG, Emery RW, Levinson MM et al. Selection of patients for cardiac transplantation. Circulation. 1987;75:1.Google Scholar
- 11.Paradis IL, Manzetti J. Medical evaluation for lung transplantation. Sem Anesthesia. 1995;14:110.Google Scholar
- 12.Kramer MR, Tiroke A, Marshall SE et al. The clinical significance of hyperbilirubenemia in patients with pulmonary hypertension undergoing heart-lung transplants. J Heart Transplant. 1990;9:79A (abstract).Google Scholar
- 15.Miller LW, Pennington DG, Kanter K, McBride L. Heart transplantation in patients over 55 years of age. J Heart Transplant. 1986;5:367.Google Scholar
- 17.Mischke L, Sisson S, Cooper DKC, Zuhdi N. Cardiac transplantation in patients age 60 years or older. J Okla State Med Assoc. (In press).Google Scholar
- 23.Robertson JA. Supply and distribution of hearts for transplantation: legal, ethical and policy issues. Circulation. 1987;75:81.Google Scholar
- 24.Holland C, Hagan M, Volkman K et al. Substance abuse: does this warrant exclusion for transplant? J Heart Transplant. 1988;7:70 (abstract).Google Scholar
- 26.Cooper DKC, Lanza RP, Barnard CN. Non-compliance in heart transplant recipients: the Cape Town experience. J Heart Transplant. 1984;3:248.Google Scholar