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Results of Cardiac Transplantation and Factors Influencing Survival based on the Registry of the International Society for Heart and Lung Transplantation and the Cardiac Transplant Research Database

  • M. R Cinquegrani
  • J. D. Hosenpud

Abstract

Despite significant progress in lengthening survival following heart transplantation (HTx) since the introduction of cyclosporin, patients who undergo this procedure do not face a normal life expectancy for their age. Information derived from a number of databases has been useful in identifying risk factors for mortality following transplantation. This chapter will review those clinical variables associated with decreased survival for heart transplant patients.

Keywords

Increase Mortality Risk Heart Lung Transplant Heart Graft High Pulmonary Vascular Resistance Multiinstitutional Study 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Hosenpud JD, Novick RJ, Breen TJ, Keck B, Daily P. The Registry of the International Society for Heart and Lung Transplantation: Twelfth Official Report-1995. Submitted.Google Scholar
  2. 2.
    Laffel GL, Barrett AI, Finkelstein S, Kaye MP. The relation between experience and outcome in heart transplantation. N Bngl J Med 1992;327:1220–5.CrossRefGoogle Scholar
  3. 3.
    Bourge RC, Naftel DC, Costanzo-Nordin MR et al. Pretransplantation risk factors for death after heart transplantation: A multiinstitutional study. The Transplant Cardiologists Research Database Group. J Heart Lung Transplant 1993; 12:549–62.PubMedGoogle Scholar
  4. 4.
    Foster ED, Fisher LD, Kaiser GC, Myers WO. Comparison of operative mortality and morbidity for initial and repeat coronary artery bypass grafting: The Coronary Artery Surgery Study (CASS) registry experience. Ann Thorac Surg 1984;38:563–70.PubMedCrossRefGoogle Scholar
  5. 5.
    Miller LW, Naftel DC, Bourge RC et al. Infection after heart transplantation: A mul-tiinstitutional study. Cardiac Transplant Research Database Group. J Heart Lung Transplant 1994;13(3):381–92.PubMedGoogle Scholar
  6. 6.
    Kobashigawa JA, Kirklin JK, Naftel DC et al. Pretransplantation risk factors for acute rejection after heart transplantation: A multiinstitutional study. The Cardiac Transplant Research Database Group. J Heart Lung Transplant 1993;12(3):355–66.PubMedGoogle Scholar
  7. 7.
    Young JB, Naftel DC, Bourge RC et al. Matching the heart donor and heart trans-plant recipient. Clues for successful expansion of the donor pool: A multivariable, multiinstitutional report. The Cardiac Transplant Research Database Group. J Heart Lung Transplant 1994;13(3):353–64.PubMedGoogle Scholar
  8. 8.
    Kirklin JK, Naftel DC, Levine TB et al. Cytomegalovirus after heart transplantation. Risk factors for infection and death: A multiinstitutional study. The Cardiac Transplant Research Database Group. J Heart Lung Transplant 1994;13(3):394–404.PubMedGoogle Scholar
  9. 9.
    Wechsler ME, Giardina EGV, Sciacca RR, Rose EA, Barr ML. Increased early mor-tality in women undergoing cardiac transplantation. N Engl J Med 1995;91:1029–35.Google Scholar
  10. 10.
    Jarcho J, Naftel DC, Shroyer TW et al. Influence of HLA mismatch on rejection after heart transplantation: A multiinstitutional study. The Cardiac Transplant Research Database Group. J Heart Lung Transplant 1994;13(4):583–95.PubMedGoogle Scholar
  11. 11.
    Keogh AM, Valantine HA, Hunt SA, Schroeder JS, Oyer PE. Increased rejection in gender-mismatched grafts: Amelioration by triple therapy. J Heart Lung Transplant 1991;10:106–10.PubMedGoogle Scholar
  12. 12.
    Terasaki P, Mickey MR, Iwaki Y et al. Long-term survival of kidney grafts. Transplant Proc. 1989;21:615–17.PubMedGoogle Scholar
  13. 13.
    Opelz G, Wujciak T. The influence of HLA compatibility on graft survival after heart transplantation. N Engl J Med 1994;330:816–19.PubMedCrossRefGoogle Scholar
  14. 14.
    Hosenpud JD, Edwards EB, Lin HM, Daily OP. The influence of HLA matching on thoracic transplant outcomes: An analysis from the UNOS/LSHLT Thoracic Registry. Submitted.Google Scholar
  15. 15.
    Butkus DE, Meydrech EF, Raju SS. Racial differences in the survival of cadaveric renal allografts. Overriding effects of HLA matching and socioeconomic factors. N Engl J Med 1992;327:840–45.PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • M. R Cinquegrani
  • J. D. Hosenpud

There are no affiliations available

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