Current Techniques of Myocardial Protection for Cardiac Transplantation

  • S. Aziz
  • A. L. Panos


Improvements in immunosuppression and pre-, peri-, and postoperative management have resulted in increased survival being obtained after heart transplantation (HTx)[1] (Chapters 43 and 44). Currently used techniques of myocardial protection for preservation of the donor heart allow only limited time for transportation between donor and recipient hospitals. Mild to moderate cardiac allograft dysfunction is not uncommon after HTx. Ischemic times greater than 5 hours are associated with increased need for inotropic support, and increased morbidity and mortality[2] (Chapters 43 and 44). Early failure of the donor heart (primary graft dysfunction) is still responsible for up to 25% of the deaths following HTx and can result from poor donor selection or inadequate organ preservation. or both[3]. The ideal method of preservation is one that will give the longest preservation time while maintaining excellent graft function. Improved methods of organ preservation should therefore demonstrate improved graft function despite a prolongation in procurement time.


Brain Death Myocardial Protection Cardiac Allograft Donor Heart Cardioplegic Solution 
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© Kluwer Academic Publishers 1996

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  • S. Aziz
  • A. L. Panos

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