Mechanical Circulatory Support Before Heart Transplantation

  • J. S. Sapirstein
  • W. E. PaeJr


Cardiac transplantation has become a standard therapy for carefully selected patients with incapacitating end-stage cardiomyopathy. Since the introduction of the procedure, refinements in organ procurement. surgical technique, and immunosuppression have prompted the loosening of recipient inclusion criteria, while at the same time generating better survival. The large numerical discrepancy between organs available for cardiac transplantation and potential recipients is well recognized[2]. Today the number of patients for whom transplantation is clinically indicated - between 10 000 and 40 000 in the USA alone[2] - far exceeds the supply of donor organs. Between 10% and 40% of waiting recipients die before a suitable heart becomes available[3], and donor supply will probably remain the major impediment to broader use of this procedure. Efforts to expand the donor pool in the future are being made[4]; currently many patients can lengthen their status as appropriate allograft candidates with mechanical circulatory assistance.


Left Ventricular Assist Device Cardiac Transplantation Centrifugal Pump Circulatory Support Ventricular Assist Device 


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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • J. S. Sapirstein
  • W. E. PaeJr

There are no affiliations available

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