The Problem of Pulmonary Hypertension in the Potential Cardiac Transplant Recipient
Despite advances in perioperative management, right-sided circulatory failure (RSCF) remains a significant source of morbidity and mortality early after cardiac transplantation. Perioperative RSCF, while clearly multifactorial in nature, has traditionally been associated with pretransplant pulmonary hypertension, as suggested by elevated pulmonary hemodynamic indices revealed on pretransplant cardiac catheterization. While severely elevated values of such indices represent a contraindication to cardiac transplantation at many centers worldwide, there currently exist no standard guidelines regarding the validity and importance of these preoperative abnormalities for postoperative outcome. The purpose of this chapter is to review the problem of pulmonary hypertension and the potential cardiac transplant recipient - its diagnosis, management and manipulation, and long-term clinical significance.
KeywordsPulmonary Hypertension Pulmonary Vascular Resistance Cardiac Transplantation Heart Lung Transplant Wood Unit
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