The Exercise Myopathy

  • Teet Seene
  • Maria Umnova
  • Priit Kaasik


The modern training of athletes is based on the overload principle and negative feedback theory: the training stimulus must be strong enough to induce disturbance of homeostasis so that the body has to initiate reactions to adapt to the training stimulus. This means that overloading is a natural part of an athletes training process and provides stimuli for adaptation and supercompensation. Imbalance in the training load-recovery relationship is the primary factor contributing to overtraining syndrome. The reflection of overtraining syndrome on the ultrastructural level of skeletal muscle has revealed that the damaging effect depends on the muscle fiber type.Due to the destruction of myofibrils and atrophy of muscle fibers, exercise myopathy develops as a result of overtraining . The most sensitive to the long-lasting exhaustive endurance exercise are fast-twitch muscle fibers. The aim of the present study was to investigate the reflection of exercise myopathy on the ultrastructural level of fast-twitch muscle fibers.


Satellite Cell Synaptic Vesicle Neuromuscular Junction Alkaline Protease Catabolic Action 
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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • Teet Seene
    • 1
  • Maria Umnova
    • 1
  • Priit Kaasik
    • 1
  1. 1.University of TartuTartuEstonia

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