Plasma Coagulation Factors

  • Pamela Sakkinen
  • Russell P. Tracy
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 193)


The role of thrombosis in precipitating acute cardiovascular disease (CVD) events has been well known since the early 1970s [1]. It is now becoming increasingly apparent that thrombosis may also be involved with the chronic development of CVD [2, 3, 4]. Clot formation or thrombosis can be conceptualized as a balance between procoagulant and anticoagulant and fibrinolytic forces C5 (Figure 2-1). Although some factors, such as thrombin, may have more than one role, this “pseudoequilibrium” provides a schema for assessing the relative coagulant balance.


Factor Versus Tissue Factor Pathway Inhibitor Plasma Fibrinogen Level Standard Heparin Phospholipid Surface 
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Copyright information

© Kluwer Academic Publishers 1997

Authors and Affiliations

  • Pamela Sakkinen
  • Russell P. Tracy

There are no affiliations available

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