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Experimental Models of Coronary Arterial Resistance and Blood Flow

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Textbook of Coronary Thrombosis and Thrombolysis

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 193))

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Abstract

In this chapter, experimental preparations that have been used to examine facets of coronary artery resistance and its effects on blood flow are reviewed. Before discussing the experimental models, the characteristics of human coronary vessel - the characteristics that we are trying to model in our experimental studies - are reviewed. Also, because most clinical problems involve restriction of blood flow through the large epicardial coronary vessels, the focus is on these large coronary arteries and not on small-vessel disease models. Remember that there are no perfect experimental models; they all have shortcomings. The biggest shortcoming is using models to address questions the models were not designed to answer.

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Authors
  1. William P. Santamore
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Editors and Affiliations

  1. Cardiovascular Thrombosis Research Center, USA

    Richard C. Becker M.D. (Director) (Director)

  2. Coronary Care Unit, University of Massachusetts Medical School, Worcester, Massachusetts

    Richard C. Becker M.D. (Director) (Director)

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© 1997 Kluwer Academic Publishers

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Santamore, W.P. (1997). Experimental Models of Coronary Arterial Resistance and Blood Flow. In: Becker, R.C. (eds) Textbook of Coronary Thrombosis and Thrombolysis. Developments in Cardiovascular Medicine, vol 193. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-33754-8_11

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  • DOI: https://doi.org/10.1007/978-0-585-33754-8_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-9923-0

  • Online ISBN: 978-0-585-33754-8

  • eBook Packages: Springer Book Archive

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