Analysis of Field Potentials and Spike Patterns Evoked by Local Electrical Stimulation of the Chicken Retina
It is well known that the retina can be stimulated in vitro and in vivo with monopolar transretinal or local bipolar applied electric current.1-4 These results indi- cate that it might be possible to develop a retina implant that electrically stimulates the remaining cells of the retinal network electrically, even if the photoreceptors are completely degenerated. Current research focuses on two different approaches for the development of an intraocular prosthesis for patients suffering from photoreceptor degeneration. Several groups favour direct electrical stimulation of retinal ganglion cell5-7 from the epiretinal side while Tassiker and Chow proposed in patents to stim- ulate neurons of the inner nuclear layer8-10 from the subretinal side (see also Zrenner et al. in this volume).
KeywordsGanglion Cell Current Pulse Inner Nuclear Layer Microelectrode Array Slow Potential
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