Grading Device for Light Perception with Retinitis Pigmentosa
Purpose: The goal of this study is to innovate a device for grading very low visual function expressed as light perception in patients such as retinitis pigmentosa (RP) and makes it possible to evaluate effects for various therapeutic modalities or their changes following the progress of the disease.
Methods: The device was composed of a pair of goggles with a white light emission diode, 5 mm in diameter, an earphone for each ear, a control cabinet which emits light and a clicking stimuli, a hand-held grip with a button, and a recorder for calculating correct answer for stimuli. The light intensity and duration were changed in three levels, 10cd/m2(C), 100C, 1000C, and its duration, 0.1second(S), 0.3S, 1S independently. As a result, they were graded into nine different levels of intensities and delivered in a random sequence after a click sound of 0.7 sec prior to the stimulation. Patients were asked to push a button when they recognized these stimuli. Each eye was separately stimulated 5 times in each intensity and duration, 45 times per eye, therefore, a total of 90 times. Ten RP patients with light perception were examined and their visual ability was graded. The FP was examined before and after cataract extraction, stellate ganglion block and lipo-prostaglandin El was administered in two cases with RP and we studied the possibility of differentiating their functions and also reproducibility with this device.
Results: We could differentiate changes of LP with this device and observe changes of very low grade vision with treatment.
Conclusion: This device is valuable for evaluating low visual function such as LP of RP patients. It will be valuable for following their vision and also discriminating very small changes of visual function with medical and surgical treatment in the future.
KeywordsVisual Function Retinitis Pigmentosa Hyperbaric Oxygen Error Score Light Perception
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