Sucralfate pp 47-58 | Cite as

Chemistry of Sucralfate

  • Kiyoshige Ochi


Sulfated polysaccharides possess antiulcer effects in experimental ulcer models and antipeptic activity in vitro. The efficacy of natural polysaccharide is closely related to the degree of the sulfation rather than the length of the sugar chain. Therefore, Namekata and co-workers investigated the antiulcer activities of the oligo- and monosaccharide sulfates whose sugar chain structures are well-known.1


Sulfur Trioxide Sulfate Moiety Hydroxyl Moiety Sucrose Molecule Oligo Saccharide Sulfate 
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Copyright information

© Plenum Press 1995

Authors and Affiliations

  • Kiyoshige Ochi
    • 1
  1. 1.Development and Technology DivisionChugai Pharmaceutical Co., Ltd.TokyoJapan

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