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Sucralfate pp 225-238 | Cite as

Sucralfate Drug Interaction Studies

  • Gilles Caillé
  • Manon Vézina

Abstract

This section reviews the literature on drug interactions with sucralfate. Since sucralfate is poorly absorbed, most of the dose remains in the gastrointestinal tract and the potential exists for sucralfate to affect the absorption of other drugs. Potential mechanisms of these interactions include adsorption, complexation, decreased dissolution resulting from altered pH, and the formation of a physical barrier to absorption.

Keywords

Healthy Male Volunteer Roxatidine Acetate Warfarin Concentration Ibuprofen Absorption Erythromycin Ethylsuccinate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press 1995

Authors and Affiliations

  • Gilles Caillé
    • 1
  • Manon Vézina
    • 2
  1. 1.Département de Pharmacologie, Faculté de MédecineUniversité de MontréalCanada
  2. 2.Département de Pharmacologie, Faculté de MédecineUniversité de Montréal, and Centre de Recherche Fernand Seguin, Hôpital Louis-HippolyteLafontaineCanada

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