Abstract
The function of CD4-positive, T helper cells is pivotal to the workings of the specific immune system. These cells direct antibody responses to protein antigens and influence cellular immunity by activating macrophages and instigating delayed-type hypersensitivity reactions. T helper cells perform these functions partially through altered expression of cell surface antigens, such as the CD40 ligand, gp39; and partially by the secretion of a large range of cytokines that have effects on various immune and hematopoetic cells.
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McKenzie, A.N.J., Heath, A.W. (1996). Interleukin 13 and Related Cytokines. In: Whetton, A.D., Gordon, J. (eds) Blood Cell Biochemistry. Blood Cell Biochemistry, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-31728-1_2
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DOI: https://doi.org/10.1007/978-0-585-31728-1_2
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