Interleukin 13 and Related Cytokines

  • Andrew N. J. McKenzie
  • Andrew W. Heath
Part of the Blood Cell Biochemistry book series (BLBI, volume 7)


The function of CD4-positive, T helper cells is pivotal to the workings of the specific immune system. These cells direct antibody responses to protein antigens and influence cellular immunity by activating macrophages and instigating delayed-type hypersensitivity reactions. T helper cells perform these functions partially through altered expression of cell surface antigens, such as the CD40 ligand, gp39; and partially by the secretion of a large range of cytokines that have effects on various immune and hematopoetic cells.


Stem Cell Factor CD40 Ligand Isotype Switching Related Cytokine Human Peripheral Blood Monocyte 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Andrew N. J. McKenzie
    • 1
  • Andrew W. Heath
    • 2
  1. 1.The MRC Laboratory of Molecular BiologyCambridgeUK
  2. 2.Department of Medical MicrobiologyUniversity of Sheffield Medical SchoolSheffieldUK

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