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The Effects of ELF on Chemical Reaction Rates in Biological Systems

  • Frank S. Barnes

Abstract

In this paper we review some of the theory and experiments associated with the effects of electric and magnetic fields at extremely low frequencies, ELF, on chemical reaction rates. The paper proposes a simple model for chemical reactions and shows that the effects of weak electric fields can change the probability that molecules of the reacting materials will encounter each other as well as shift the barrier energy for the reaction. These effects occur primarily in the vicinity of membranes or at boundaries where there are large variations in current density or the concentration of one of the chemical reactants.

Keywords

Current Flow Drift Velocity Collision Frequency Space Charge Layer Diffusion Control Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    N. Wertheimer, E Leeper “Electrical Wiring Configurations and Childhood Cancer” American Journal of Epidemiology, Vol. 109, No. 3, 1979Google Scholar
  2. 2.
    D. Savitz, H. Wachtel. F. Bames, E. John and J. Tvrdik, “Case-Control Study of Childhood Cancer and Exposure to 60 Hz Magnetic Fields” American Journal Epidemiology, Vol.128, No. 1, 21–38, 1988Google Scholar
  3. 3.
    S.J. London, D.C. Thomas, J.D. Bowman, E. Sobel, J.M. Peters, “Exposure to Residential Electric and Magentic Fields and Risk of Childhood Leukemia” American Journal of Epidemiology, Vol. 134, 923–937, 1991Google Scholar
  4. 4.
    M. Feychting, A. Ahlbom, “Magnetic Fields and Cancer in People Residing Near Swedish High Voltage Power Lines” IMM Report 6/92, Karolinska Institute, Stockholm, SwedenGoogle Scholar
  5. 5.
    F.S. Barnes “Typical Electric and Magnetic Field Exposures at Power Line Frequencies and Their Coupling to Biological Systems” Advances in Chemistry Series No. 250, Biological Effects of Environmental Electromagnetic Fields, Martin Blank, Ed., American Chemical Society Books, Washington DC. to be published 1995Google Scholar
  6. 6.
    W. T. Kaune and W. C. Forsythe, “Current Densities Measured in Human Models Exposed to 60 Hz Electric Fields.” Bioelectromagnetics, Vol. 6, 13–32, 1985CrossRefGoogle Scholar
  7. 7.
    T.S. Tenforde and W.T. Kaune, “Interaction of Extremely Low Frequency Electric and Magnetic Fields with Humans”, Health Physics, Vol. 53, No. 6, 583–606, December 1987. Special Section: Non-Ionizing RadiationCrossRefGoogle Scholar
  8. 8.
    F. X. Hart, K. Cvely, C. D. Finch, “Use of a Spreadsheet Program to Calculate the Electric Field Current Density Distributions Induced in Irregularly Shaped. Inhomogeneous Biological Structures by Low-Frequency Magnetic Fields” Bioelectromagnetics, Vol. 14, No. 2, 161–172, 1993CrossRefGoogle Scholar
  9. 9.
    F. S. Barnes “Interaction of DC and ELF Electric Fields with Biological Materials and Systems” The CRC Handbook of Biological Effects of Electromagnetic Fields Charles Polk and Elliot Postow, Eds., CRC Press, Boca Raton, Florida, 1986 and Second Addition to be published 1995Google Scholar
  10. 10.
    Steven S. Zumdahl, Chemistry Second Edition page 546 D. C.Heath Co Lexington Mass, 1989Google Scholar
  11. 11.
    P.W. Atkins. Physical Chemistry Fourth Ed., See Chapter 27 for a more complete discussion. Publisher W. H. Freeman Co. N.Y. 1990Google Scholar
  12. 12.
    L. Onsager, “Deviations from Ohm’s Law in Weak Electrolytes” J. of Chem. Phys. Vol. 2, 599–615, 1934CrossRefGoogle Scholar
  13. 13.
    R.J. MacGregor, ER. Lewis, Neural Modelling, Plenum Press. New York. 1977Google Scholar
  14. 14.
    Y.J. Seto, S.T. Hsieh, “Electromagnetic Induced Kinetic Effects on Charged Substrates in Localized Enzyme Systems” Biotechnololgy and Bioengineering Vol. XVIII, 813–837, 1976CrossRefGoogle Scholar
  15. 15.
    B. Robertson and R.D. Astumian, “Frequency and Amplitude Dependence of the Effect of a Weak Oscillating Field on Biological Systems” in Charge and Field Effects in Biological Systems-3, M. Allen, S.F. Cleary, A. Sowers and D.F. Shillady, Eds., Birkhauser, 1992Google Scholar
  16. 16.
    R.D. Astumian and B. Robertson, “Nonlinear Effect of an Oscillating Electric Field on Membrane Proteins” J. Chem. Phys. Vol. 91, No. 8, 15 October 1989Google Scholar
  17. 17.
    B. Robertson and R.D. Astumian, “Frequency Dependence of Catalyzed Reactions in a Weak Oscillating Field” J. Chem. Phys. Vol. 94, No. 11, 1 June 1991Google Scholar
  18. 18.
    T.Y. Tsong. R.D. Astumian, “Electroconformational Coupling: How Membrane-Bound ATPase Transduces Energy from Dynamic Electric Fields” Ann. Rev. Physiol. Vol. 50, 273–290, 1988CrossRefGoogle Scholar
  19. 19.
    R.D. Astumian and B. Robertson “Imposed Oscillations of Kinetic Barriers Can Cause an Enzyme to Drive a Chemical Reaction Away from Equilibrium” J. of the Amer. Chem. Soc. Vol. 115, No. 24, 11063–11068, 1993CrossRefGoogle Scholar
  20. 20.
    T.Y. Tsong, D.S. Liu, R. Chauvin, “Electroconformational Coupling (ECC): An Electric Field Induced Enzyme Oscillation for Cellular Energy and Signal Transductions” Bioelectrochemistry and Bioenergetics, Vol. 21, 319–331, 1989CrossRefGoogle Scholar
  21. 21.
    D.S. Liu, R.D. Astumian, T.Y. Tsong. “Activation of Na+and K+Pumping Modes of (na. K)-ATPase by an Oscillating Electric Field” J. of Bio. Chem., Vol. 265, No. 13, 7260–7267, 1990Google Scholar
  22. 22.
    A. Raudino and R. Larter. “Enhancement of Sorption Kinetics by an Oscillatory Electric Field” J. Chem. Phys. Vol. 98. No. 4, 15 February 1993Google Scholar
  23. 23.
    A. Graziana, R. Ranjeva and J. Teissie, “External Electric Fields Stimulate the Electrogenic Calcium Sodium Exchange in Plant Protoplasts” Biochemistry, Vol. 29, 8313–8318, 1990.CrossRefGoogle Scholar
  24. 24.
    R.D. Astumian. J.C. Weaver and R.K. Adair, “Rectificuation and Signal Averaging of Weak Electric Fields by Biological Cells” Proc. Natl. Acad. Sci. USA in press 1995Google Scholar
  25. 25.
    R.D. Astumian and M. Bier. “Fluctuation Driven Ratchets: Molecular Motors” Vol. 72, No. 11, Physical Review Letters, 14 March 1994Google Scholar
  26. 26.
    F.S. Barnes, “Some Engineering Models for Interactions of Electric and Magnetic Fields With Biological Systems” Bioelectromagnetics Supplement Vol. 1, 67–85, 1992CrossRefGoogle Scholar

Copyright information

© Plenum Press 1996

Authors and Affiliations

  • Frank S. Barnes
    • 1
  1. 1.Department of Electrical and Computer EngineeringUniversity of ColoradoBoulder

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