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Partial Left Ventriculectomy

  • Richard J. Kaplon
  • Patrick M. McCarthy
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 225)

Abstract

End-stage heart failure currently affects 1 % of people under 55 years old, 9% of people over 80 years old, and is expected to continue to increase in prevalence.1 Despite improvements in pharmacologic management of heart failure with newer agents such as angiotensin-converting enzyme inhibitors or beta-blockers such as carvedilol, approximately 25% of patients die while awaiting heart transplantation. 2-4 Even with attempts at expanding the donor pool through “alternate recipient lists”, the limited number of hearts available for transplantation has plateaued.5,6 Ventricular-assist devices (VAD) have been effective as bridges to transplantation for those patients refractory to medical therapy, however, present use of VADs as destination therapy remains investigational.7-9 Clinical attempts at cardiomyoplasty and xenotransplantation have, thus far, been generally disappointing.10,11

Keywords

Cardiac Index Papillary Muscle Mitral Valve Repair Mitral Leaflet Bovine Pericardium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • Richard J. Kaplon
  • Patrick M. McCarthy

There are no affiliations available

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