Selection of transport parameters in judging membrane performance

  • Lee W. Henderson
Part of the Developments in Nephrology book series (DINE, volume 39)


The measurement of solute clearance has historical roots for the nephrologist and has contributed materially to the quantitative understanding of the performance of the native kidney in both glomerular and tubular function [1]. The logic then of designing an analogous term for use with the artificial kidney was persuasive for AN. Wolf et al. [2]. While initially helpful the interpretation of artificial kidney clearance has become overly complex as a result of the proliferation of artificial kidney techniques with subsequent “customization” of the clearance term for the new techniques. This has led to confusion and conceptual errors in intermodality comparisons of performance and outcome when clearance based terms like Kt/V urea are used to quantitate the amount of therapy rendered [3].


Peritoneal Dialysis Continuous Ambulatory Peritoneal Dialysis Native Kidney Plasma Water Artificial Kidney 


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© Kluwer Academic Publishers 1999

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  • Lee W. Henderson

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