Selection of adequacy criteria models for hemodialysis

  • William R. Clark
Part of the Developments in Nephrology book series (DINE, volume 39)


For the past several years, the topic of hemodialysis (HD) adequacy has been one of the most widely discussed and investigated subjects in all of ESRD therapy. However, considerable disagreement on several fundamental issues in HD adequacy, including the defining criteria, persist. Although this topic has been reviewed extensively in the literature [1-5], this vitally important aspect of the care of the chronic HD patient has not been critically assessed from a quality assurance perspective. The purpose of this chapter is first to provide a clinical overview, including a brief review of landmark studies that provide the basis for current HD adequacy recommendations. The remainder of the chapter deals with implementation of these current recommendations and the quality assurance issues the chronic dialysis unit must consider.


Dialysis Dose Middle Molecule Protein Catabolic Rate Urea Reduction Ratio Spend Dialysate 
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© Kluwer Academic Publishers 1999

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  • William R. Clark

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