Abstract
Drugs used in anesthesia are all bound to a greater or lesser degree to plasma proteins. Plasma protein binding of drugs has a significant effect on their kinetics and dynamics. Variations of normal physiology and diseases affect both the concentrations and affinity of plasma proteins for drugs. This chapter provides a brief discussion of the relevance of plasma protein drug binding to kinetics and dynamics.
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© 1992 Kluwer Academic Publishers
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Woerlee, G.M. (1992). Plasma Protein Binding. In: Kinetics and Dynamics of Intravenous Anesthetics. Developments in Critical Care Medicine and Anesthesiolgy, vol 26. Springer, Dordrecht. https://doi.org/10.1007/978-0-585-28009-7_8
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DOI: https://doi.org/10.1007/978-0-585-28009-7_8
Publisher Name: Springer, Dordrecht
Print ISBN: 978-0-7923-1506-3
Online ISBN: 978-0-585-28009-7
eBook Packages: Springer Book Archive