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Plasma Protein Binding

  • Gerald M. Woerlee
Part of the Developments in Critical Care Medicine and Anesthesiolgy book series (DCCA, volume 26)

Abstract

Drugs used in anesthesia are all bound to a greater or lesser degree to plasma proteins. Plasma protein binding of drugs has a significant effect on their kinetics and dynamics. Variations of normal physiology and diseases affect both the concentrations and affinity of plasma proteins for drugs. This chapter provides a brief discussion of the relevance of plasma protein drug binding to kinetics and dynamics.

Keywords

Plasma Protein Binding Plasma Drug Concentration Free Fraction Extracellular Fluid Volume Protein Drug Binding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1992

Authors and Affiliations

  • Gerald M. Woerlee
    • 1
  1. 1.Rijnoord HospitalAlphen aan den RijnThe Netherlands

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