Transplant Survival: Follow-up of Highly Sensitized and Control Renal Grafts Transplanted 1982 to 1985

Abstract

Eight European registries - Eurotransplant, France Transplant, Hispano and Luso Transplant, North Italy Transplant, Scandia Transplant, Swiss Transplant, UK Transplant - collaborated to establish a database of highly sensitized and control renal grafts. Each registry identified recipients who were transplanted between 1982 and 1985 and whose peak reaction frequency prior to the index graft was more than 80%. For each such graft, a control transplant was selected, matched for recipient sex, year of transplant, first versus regraft, and transplant centre. Controls for highly sensitized first grafts required to have peak reaction frequency of at most 10%. Controls for highly sensitized regrafts were eligible if peak reaction frequency prior to the index graft was at most 30%.