Organelles of Filamentous Fungi

  • P. Markham


Filamentous fungi are typical eukaryotes in many respects and contain a wide range of membrane-bounded subcellular compartments which are the sites of specialised functions. These are organelles as defined by the possession of a bounding membrane. Filamentous fungi contain all the major organelles with the key exception of the chloroplast, which is absent from all of these non-photosynthetic organisms. In addition, the occurrence of a structurally identifiable Golgi apparatus, with the classic dictyosome organization of stacked disc-shaped cisternae, is rare among filamentous fungi. It is common only in the Mastigomycotina, most notably in the class Oomycetes (CR9 et al., 1974), a group which shows many affinities with algae and may only be tenuously related to most filamentous fungi (CR7, 1987; CR20, 1987a, CR20, 1987b). A comparison of the genomic sequences coding for small-subunit ribosomal RNA has indicated that Oomycetes, represented by Achlya bisexualis, are very closely related to the chrysophytes (golden-brown algae) and show far less similarity to green algae or to ascomycete fungi (CR41 et al., 1987).


Filamentous Fungus Neurospora Crassa Aspergillus Nidulans Hexagonal Crystal Penicillium Chrysogenum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Alberts, B., Bray, D., Lewis, J. et al. (1989) Molecular Biology of the Cell, 2nd edn, Garland New York.Google Scholar
  2. Aoki, S., Ito-Kuwa, S., Nakamura, Y. and Masuhara, T. (1989) Mitochondrial behaviour during the yeast-hypha transition of Candida albkans. Microbios, 60, 79–86.PubMedGoogle Scholar
  3. Aylmore, R.C. and Todd, N.K. (1984) Hyphal fusion in Coriolus versicolor, in The Ecology and Physiology of the Fungal Mycelium, (eds D.H. Jennings and A.D.M. Rayner), Cambridge University Press, Cambridge, pp. 103–25.Google Scholar
  4. Aylmore, R.C., Wakley, G.E. and Todd, N.K. (1984) Septal sealing in the basidiomycete Coriolus versicolor. Journal of General Microbiology, 130, 2975–82.Google Scholar
  5. Bartnicki-Garcia, S., Ruiz-Herrera, J. and Bracker, C. (1979) Chitosomes and chitin synthesis, in Fungal Walls and Hyphal Growth, (eds J.H. Burnett and A.P.J. Trinci), Cambridge University Press, Cambridge, pp. 149–68.Google Scholar
  6. Beakes, G.W. (1981) Ultrastructure of the phycomycete nucleus, in The Fungal Nucleus, (eds K. Gull and S.G. Oliver), Cambridge University Press, Cambridge, pp. 1–35.Google Scholar
  7. Beakes, G.W. (1987) Oomycete phylogeny: ultrastructural perspectives, in Evolutionary Biology of the Fungi, (eds A.D.M. Rayner, CM. Brasier and D. Moore), Cambridge University Press, Cambridge, pp. 405–21.Google Scholar
  8. Beckett, A. (1981) The ultrastructure of septal pores and associated structures in the ascogenous hyphae and asci of Sordaria humana. Protoplasma, 107, 127–47.CrossRefGoogle Scholar
  9. Beckett, A., Heath, I.B. and McLaughlin, DJ. (1974) An Atlas of Fungal Ultrastructure, Longman, London.Google Scholar
  10. Blayney, P.G. and Marchant, R. (1977) Glycogen and protein inclusions in elongating stipes of Coprinus cinereus. Journal of General Microbiology, 98, 467–76.CrossRefGoogle Scholar
  11. Bracker, C., Ruiz-Herrera, J. and Bartnicki-Garcia, S. (1976) Structure and transformation of chitin synthetase particles (chitosomes) during microfibrils synthesis in vitro. Proceedings of the National Academy of Sciences, USA, 73, 4570–4.CrossRefGoogle Scholar
  12. Brenner, D.M. and Carroll, G.C. (1968) Fine-structure correlates of growth in hyphae of Ascodesmis sphaerospora. Journal of Bacteriology, 95, 658–71.PubMedGoogle Scholar
  13. Buller, A.H.R. (1933) Researches in Fungi, vol. V, Hafner, New York.Google Scholar
  14. Burnett, J.H. (1976) Fundamentals of Mycology, 2nd edn, Edward Arnold, London.Google Scholar
  15. Butt, T.M., Beckett, A. and Wilding, N. (1981) Protoplasts in the in vivo life cycle of Erynia neoaphidis. Journal of General Microbiology, 127, 417–21.Google Scholar
  16. Cantino, E.C. and Mills, G.L. (1979) The gamma particle in Blastocladiella emersonii: what is it?, in Viruses and Plasmids in Fungi, (ed. P. Lemke), Marcel Dekker, New York, pp. 441–84.Google Scholar
  17. Carbonell, L.M. (1969) Ultrastructure of dimorphic transformation in Paracoccidioides brasiliensis. Journal of Bacteriology, 100, 1076–2.PubMedGoogle Scholar
  18. Carlile, M.J. (1980) From prokaryote to eukaryote: gains and losses, in The Eukaryotic Microbial Cell, (eds G.W. Gooday, D. Lloyd and A.P.J. Trinci), Cambridge University Press, Cambridge University Press, Cambridge, pp. 1–40.Google Scholar
  19. Carson, D.B. and Cooney, J.J. (1990) Microbodies in fungi: a review. Journal of Industrial Microbiology, 6, 1–18.CrossRefGoogle Scholar
  20. Cavalier-Smith, T. (1987a) The origin of fungi and pseudofungi, in Evolutionary Biology of the Fungi, (eds A.D.M. Rayner, C.M. Brasier and D. Moore), Cambridge University Press, Cambridge, pp. 339–53.Google Scholar
  21. Cavalier-Smith, T. (1987b) The kingdom Chromista: origin and systematics, in Progress in Phycological Research, Vol. 4 (eds F.E. Round and D.J. Chapman), Biopress, Bristol, pp. 309–47.Google Scholar
  22. Clutterbuck, A.J. (1969) Cell volume per nucleus in haploid and diploid strains of Aspergillus nidulans. Journal of General Microbiology, 55, 291–9.PubMedCrossRefGoogle Scholar
  23. Cole, G.T. (1986) Models of cell differentiation in conidial fungi. Microbiological Reviews, 50, 95–132.PubMedGoogle Scholar
  24. Cole, G.T. and Samson, R.A. (1979) Patterns of Development in Conidial Fungi. Pitman, London.Google Scholar
  25. Collinge, A.J. and Markham, P. (1982) Hyphal tip ultrastructure of Aspergillus nidulans and Aspergillus giganteus and possible implications of Woronin bodies close to the hyphal apex of the latter species. Protoplasma, 113, 209–13.CrossRefGoogle Scholar
  26. Collinge, A.J. and Markham, P. (1985) Woronin bodies rapidly plug septal pores of severed Penicillium chrysogenum hyphae. Experimental Mycology, 9, 80–5.CrossRefGoogle Scholar
  27. Collinge, A.J. and Markham, P. (1987) Nuclei plug septal pores in severed hyphae of Sordaria brevicollis. FEMS Microbiology Letters. 44, 85–90.CrossRefGoogle Scholar
  28. Collinge, A.J. and Markham, P. (1992) Ultrastructure of hyphal tip bursting in Penicillium chrysogenum. FEMS Microbiology Letters, 91, 49–54.CrossRefGoogle Scholar
  29. Collinge, A.J. and Trinci, A.P.J. (1974) Hyphal tips of wild type and spreading colonial mutants of Neurospora crassa. Archiv für Mikrobiologie, 99, 353–68.Google Scholar
  30. Ebersold, H.R., Cordier, J-L. and Luthy, P. (1981) Bacterial mesosomes: method dependent artifacts. Archives of Microbiology, 130, 19–22.PubMedCrossRefGoogle Scholar
  31. Flores-Martinez, A., Lopez-Romero, E., Martinez, J.P. et al., (1990) Protein composition of purified chitosomes of Mucor rouxii. Experimental Mycology, 14, 160–8.CrossRefGoogle Scholar
  32. Fuller, M.S. (1966) Structure of the uniflagellate zoospores of aquatic phycomycetes, in The Fungus Spore, (ed M.F. Madelin), Butterworths, London, pp. 67–92.Google Scholar
  33. Garrison, R.G., Lane, J.W. and Field, M.F. (1970) Ultrastructural changes during the yeastlike to mycelialphase conversion of Blastomyces dermatitidis and Histoplasma capsulatum. Journal of Bacteriology, 101, 628–35.PubMedGoogle Scholar
  34. Girbardt, M. (1969) Die Ultrastruktur der Apikalregion von Pilzhyphen. Protoplasma, 67, 413–41.CrossRefGoogle Scholar
  35. Gooday, G.W. and Trinci, A.P.J. (1980) Wall structure and biosynthesis in fungi, in The Eukaryotic Microbial Cell, (eds. G.W. Gooday, D. Lloyd and A.P.J. Trinci), Cambridge University Press, Cambridge, pp. 207–51.Google Scholar
  36. Gow, N.A.R. and Gooday, G.W. (1982) Vacuolation, branch production and linear growth of germ tubes of Candida albicans. Journal of General Microbiology, 128, 2195–8.PubMedGoogle Scholar
  37. Gow, N.A.R. and Gooday, G.W. (1984) A model for the germ tube formation and mycelial growth form of Candida albicans. Sabouraudia, 22, 137–43.PubMedCrossRefGoogle Scholar
  38. Gray, S.N., Wilding, N. and Markham, P. (1991) In vitro germination of single conidia of the aphid-pathogenic fungus Erynia neoaphidis and phenotypic variation among sibling strains. FEMS Microbiology Letters, 79, 273–8.CrossRefGoogle Scholar
  39. Grove, S.N. (1978) The cytology of hyphal tip growth, in The Filamentous Fungi vol. III, Developmental Mycology, (eds J.E. Smith and D.R. Berry), Edward Arnold, London, pp. 28–50.Google Scholar
  40. Gull, K. (1978) Form and function of septa in filamentous fungi, in The Filamentous Fungi, vol. III, Developmental Mycology, (eds J.E. Smith and D.R. Berry), Edward Arnold, London, pp. 78–93.Google Scholar
  41. Gunderson, J.H., Elwood, H., Ingold, A. et al., (1987) Phylogenetic relationships between chlorophytes, chrysophytes, and oomycetes. Proceedings of the National Academy of Sciences, USA, 84, 5823–7.CrossRefGoogle Scholar
  42. Head, J.B. (1987) The isolation and characterization of hexagonal crystals of Neurospora crassa and Woronin bodies of Penicillium chrysogenum, PhD thesis, University of London.Google Scholar
  43. Head, J.B., Markham, P. and Poole, R.K. (1989) Woronin bodies from Penicillium chrysogenum: isolation and characterization by analytical subcellular fractionation. Experimental Mycology, 13, 203–11.CrossRefGoogle Scholar
  44. Hernandez, J., Lopez-Romero, E., Cerbon, J. and Ruiz-Herrera, J (1981) Lipid analysis of chitosomes, chitinsynthesizing microvesicles from Mucor rouxii. Experimental Mycology, 5, 349–56.CrossRefGoogle Scholar
  45. Hoch, H.C. and Maxwell, D.P. (1974) Proteinaceous hexagonal inclusions in hyphae of Whetzelinia sclerotiorum and Neurospora crassa. Canadian Journal of Microbiology, 20, 1029–35.PubMedCrossRefGoogle Scholar
  46. Hoch, H.C., Tucker, B.E. and Staples, R.C. (1987) An intact microtubule cytoskeleton is necessary for mediation of the signal for cell differentiation in Uromyces. European Journal of Cell Biology, 45, 209–18.Google Scholar
  47. Hohn, T.M., Lovett, J.S. and Bracker, C.E. (1984) Characterization of the major proteins in gamma particles, cytoplasmic organelles in Blastocladiella emersonii zoospores. Journal of Bacteriology, 158, 253–63.PubMedGoogle Scholar
  48. Howard, R.J. (1981) Ultrastructural analysis of hyphal tip cell growth in fungi: Spitzenkorper, cytoskeleton and endomembranes after freeze-substitution. Journal of Cell Science, 48, 89–103.PubMedGoogle Scholar
  49. Howard, R.J. and Aist, J.R. (1977) Effects of MBC on hyphal tip organization, growth, and mitosis of Fusarium acuminatum, and their antagonism by D2O. Protoplasma, 92, 195–210.PubMedCrossRefGoogle Scholar
  50. Howard, R.J. and Aist, J.R. (1979) Hyphal tip cell ultrastructure of the fungus Fusarium: improved preservation by freeze-substitution. Journal of Ultrastructure Research, 66, 224–34.PubMedCrossRefGoogle Scholar
  51. Howard, R.J. and Aist, J.R. (1980) Cytoplasmic microtubules and fungal morphogenesis: ultrastructural effects of methyl benzimidazole-2-ylcarbamate determined by freeze-substitution of hyphal tips. Journal of Cell Biology, 87, 55–64.PubMedCrossRefGoogle Scholar
  52. Hunsley, D. and Gooday, G.W. (1974) The structure and development of septa in Neurospora crassa. Protoplasma, 82, 125–46.PubMedCrossRefGoogle Scholar
  53. Jackson, C.W. and Heale, J.B. (1985) Relationship between DNA content and spore volume in sixteen isolates of Verticillium lecannii and two new diploids of V, dahliae (= V. dahliae var longisporum Stark). Journal of General Microbiology, 131, 3229–36.Google Scholar
  54. Kanaseki, T., and Kadota, K. (1969) The ‘vesicle in a basket’. A morphological study of the coated vesicle isolated from the nerve endings of the guinea pig brain, with special reference to the mechanism of movements. Journal of Cell Biology, 42, 202–20.PubMedCrossRefGoogle Scholar
  55. Keller, G-A., Krisans, S., Gould, S.J. et al. (1991) Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes. Journal of Cell Biology, 114, 893–904.PubMedCrossRefGoogle Scholar
  56. King, S.B. and Alexander, L.J. (1969) Nuclear behavior, septation and hyphal growth of Altemaria solani. Journal of General Microbiology, 67, 125–33.Google Scholar
  57. Klionsky, D.J., Herman, P.J. and Emr, S.D. (1990) The fungal vacuole: composition, function, and biogenesis. Microbiological Reviews, 54, 266–92.PubMedGoogle Scholar
  58. Lane, J.W. and Garrison, R.G. (1970) Electron microscopy of the yeast to mycelial phase conversion of Sporotrichum schenckii. Canadian Journal of Microbiology, 16, 747–9.PubMedCrossRefGoogle Scholar
  59. Lindmark, D.G. and Muller, M. (1973) Hydrogenosome, a cytoplasmic organelle of the anaerobic flagellate, Tritrichotnonas foetus, and its role in pyruvate metabolism. Journal of Biological Chemistry, 248, 7724–8.PubMedGoogle Scholar
  60. Lloyd, D. and Turner, G. (1980) Structure, function, biogenesis and genetics of mitochondria, in The Eukaryotic Microbial Cell, (eds, G.W. Gooday, D. Lloyd and A.P.J. Trinci), Cambridge University Press, Cambridge, pp. 143–80.Google Scholar
  61. Markham, P. and Collinge, A.J. (1987) Woronin bodies of filamentous fungi. FEMS Microbiology Reviews, 46, 1–11.CrossRefGoogle Scholar
  62. Markham, P. Collinge, A.J., Head, J.B. and Poole, R.K. (1987) Is the spatial organization of fungal hyphae maintained and regulated by Woronin bodies? in Spatial Organization in Eukaryotic Microbes (eds R.K. Poole and A.P.J. Trinci), IRL Press, Oxford, pp. 79–99.Google Scholar
  63. Mason, P.J. and Crosse, R. (1975) Crystalline inclusions in hyphae of the glaucus group of Aspergilli. Transactions of the British Mycological Society, 65, 129–34.CrossRefGoogle Scholar
  64. Maxwell, D.P., Armentrout, V.N. and Graves, L.B. (1977) Microbodies in plant pathogenic fungi. Annual Review of Phytopathology, 15, 119–34.CrossRefGoogle Scholar
  65. McClure, W.K., Park, D. and Robinson, P.M. (1968) Apical organization in the somatic hyphae of fungi. Journal of General Microbiology, 50, 177–82.PubMedCrossRefGoogle Scholar
  66. McKeen, W.E. (1971) Woronin bodies in Erysiphe graminis DC. Canadian Journal of Microbiology, 17, 1557–60.PubMedCrossRefGoogle Scholar
  67. McKerracher, L.J. and Heath, I.B. (1987) Cytoplasmic migration and intracellular organelle movements during tip growth of fungal hyphae. Experimental Mycology, 11, 79–100.CrossRefGoogle Scholar
  68. Moore, R.T. (1985) The challenge of the dolipore/parenthesome septum, in Developmental Biology of Higher Fungi, (eds D. Moore, L.A. Casselton, D.A. Wood and J.C. Frankland), Cambridge University Press, Cambridge, pp. 175–212.Google Scholar
  69. Moore, R.T. and McAlear, J.M. (1961) Fine structure of mycota, 5. Lomasomes — previously uncharacterised hyphal structures. Mycologia, 53, 194–200.CrossRefGoogle Scholar
  70. Müller, M. (1980) The hydrogenosome, in The Eukaryotic Microbial Cell, (eds G.W. Gooday, D. Lloyd and A.P.J. Trinci), Cambridge University Press, Cambridge, pp. 127–42.Google Scholar
  71. Nguyen, T.T. and Niederpruem, D.J. (1984) Hyphal interactions in Schizophyllum commune: the di-mon mating, in The Ecology and Physiology of the Fungal Mycelium, (eds D.H. Jennings and A.D.M. Rayner), Cambridge University Press, Cambridge, pp. 73–102.Google Scholar
  72. Oakley, B.R. and Rinehart, J.E. (1985) Mitochondria and nuclei move by different mechanisms in Aspergillus nidulans. Journal of Cell Biology, 101, 2392–7.PubMedCrossRefGoogle Scholar
  73. Oujezdsky, K.B., Grove, S.N. and Szaniszlo, P.J. (1973) Morphological and structural changes during the yeast-to-mold conversion of Phialophora dermatitidis. Journal of Bacteriology, 113, 468–77.PubMedGoogle Scholar
  74. Pearse, B.M.F. (1976) Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles. Proceedings of the National Academy of Sciences, USA, 73, 1255–9.CrossRefGoogle Scholar
  75. Robertson, N.F. (1965) The fungal hypha. Transactions of the British Mycological Society, 48, 1–8.CrossRefGoogle Scholar
  76. Ross, I.K. (1976) Nuclear migration rates in Coprinus congregatus: a new record. Mycologia, 68, 418–22.CrossRefGoogle Scholar
  77. Sewall, T.C., Roberson, R.W. and Pommerville, J.C. (1989) Identification and characterization of Golgi equivalents from Allomyces macrogynus. Experimental Mycology, 13, 239–52.CrossRefGoogle Scholar
  78. That, T.C.C-T., Hoang-Van, K., Turian, G. and Hoch, H.C. (1987) Isolation and characterization of coated vesicles from filamentous fungi. European Journal of Cell Biology, 43, 189–94.PubMedGoogle Scholar
  79. Theodorou, M.K., Lowe, S.E. and Trinci, A.P.J. (1992) Anaerobic fungi and the rumen ecosystem, in The Fungal Community. Its Organization and Role in the Ecosystem, 2nd edn, (eds G.C. Carroll and D.T. Wicklow), Marcel Dekker, New York, pp. 43–72.Google Scholar
  80. Todd, N.K. and Aylmore, R.C. (1985) Cytology of hyphal interactions and reactions in Schizophyllum commune, in Developmental Biology of Higher Fungi, (eds D. Moore, L.A. Casselton, D.A. Wood and J.C. Frankland), Cambridge University Press, Cambridge, pp. 231–18.Google Scholar
  81. Trinci, A.P.J. (1979) The duplication cycle and branching in fungi, in Fungal Walls and Hyphal Growth, (eds J.H. Burnett and A.P.J. Trinci), Cambridge University Press, Cambridge, pp. 319–58.Google Scholar
  82. Trinci, A.P.J. and Collinge, A.J. (1973) Structure and plugging of septa in wild-type and spreading colonial mutants of Neurospora crassa. Archiv für Mikrobiologie, 91, 355–64.PubMedCrossRefGoogle Scholar
  83. Trinci, A.P.J. and Collinge, A.J. (1974) Occlusion of the septal pores of damaged hyphae of Neurospora crassa by hexagonal crystals. Protoplasma 80, 57–67.PubMedCrossRefGoogle Scholar
  84. Typas, M.A. and Heale, J.B. (1977) Analysis of ploidy levels in strains of Verticillium using a Coulter counter. Journal of General Microbiology, 101, 177–80.CrossRefGoogle Scholar
  85. Webster, J. (1980) Introduction to Fungi, 2nd edn, Cambridge University Press, Cambridge.Google Scholar
  86. Wood, D.A., Craig, G.D., Atkey, P.T. et al. (1985) Ultrastructural studies on the cultivation processes and growth and development of the cultivated mushroom Agaricus bisporus. Food Microstructure, 4, 143–64.Google Scholar
  87. Yarlett, N., Orpin, C.G., Munn, E.A. et al. (1986) Hydrogenosomes in the rumen fungus Neocallimastix patriciarum. Biochemical Journal, 236, 729–39.PubMedGoogle Scholar

Copyright information

© Neil A.R. Gow and Geoffrey M. Gadd 1995

Authors and Affiliations

  • P. Markham
    • 1
  1. 1.Microbiology DepartmentKing’s CollegeLondonUK

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