Some of the most powerful methods of gathering data in the cell culture laboratory use visual observation. While it can take a good deal of time to develop techniques to transfer the visual observations into quantitative data, these numbers frequently still do not convey the qualitative information conveyed by visual observation. Visual observation thus remains an invaluable tool of the experienced cell culturist and cell biologist in gathering information on the status of cultures and experiments. This information is extremely valuable in making the ongoing decisions involved in establishing cell lines, maintaining healthy cultures in the laboratory, and deciding which lines of research to pursue. A trained eye and the knowledge base to interpret the observed phenomenon are therefore assets to any cell biologist.


Light Microscope Level Inverted Phase Contrast Microscope Subcellular Component Phase Ring Tissue Culture Supernatant 
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© Plenum Press, New York 1998

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