Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)
Atherosclerosis, the main cause of heart attacks, stroke, and gangrene of the extremities, is a disease of the medium and large arteries. It often begins early in life and progresses in a series of stages throughout adulthood. This progression, as shown in Fig. 6.1, begins with some form of injury or disturbance to the normal flow of blood near the arterial wall, and with an accumulation of cholesterol in that region. These two abnormalities combine to produce inflammation.
KeywordsShear Stress Tight Junction Wall Shear Stress Fluid Shear Stress Leukocyte Rolling
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